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Downloaded from
YTS.BZ
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Official YIFY movies site:
YTS.BZ
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Okay.
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Oh, that's so good.
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.
Um, one more time.
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Look towards me.
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And action, Cindy.
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I took on the government
for women's sexual pleasure,
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and I won.
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Let me tell you why I did it.
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The single biggest crisis
in women's health is
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that you are not
taken seriously.
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Why at your age should you
still be concerned about sex?
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.
Ladies and gentlemen, stand up on your feet
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and give a wild 10X welcome
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to Cindy Eckert!
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How many of you,
before this very moment,
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knew there was a little
pink pill for women?
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Not so many of you.
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So I have to ask the
obvious question:
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How many of you knew there was
a little blue pill for men?
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.
Oh, all of you know that.
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Okay.
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.
It's known as Viagra for women,
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a tiny tablet that could have
a huge impact in the bedroom.
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.
This quest to get a female sex pill
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has been going on
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for years and
years and years.
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The drug comes
with side effects.
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The FDA has
rejected it twice.
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This whole fight has been about
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getting women what we deserve.
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Addressing low desire
and sexual health in women
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is very similar to the
fight that's happening
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in reproductive health.
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It's all the same message:
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We don't deserve to
control our own bodies.
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.
A new study released today raises big questions
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about whether or not it should
have been approved for women
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to use at all.
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.
I've heard every single thing.
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I've been told
not to wear pink,
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pull your hair back,
take the makeup off.
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No one will take
you seriously.
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.
Will the FDA approve
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the so-called female
Viagra drug for women
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with unhappy sex lives?
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Our very first
meeting with the FDA,
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a gentleman in the room said,
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"What do we need a bunch of
horny women running around for?"
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What?
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If there were clear evidence of
a clinically meaningful benefit,
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which I don't believe there is,
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approval might be appropriate.
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.
All of that fed the frenzy.
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But at the heart of
that is really our bias.
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In every scenario we're
gonna talk about here today,
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you can just
think to yourself,
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but what if the
pill had been blue?
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.
Clamour for Viagra worldwide.
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.
For men suffering from impotence
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Viagra has
been hailed
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as a miracle drug.
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.
It's the first pill ever developed
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to treat impotence.
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Pfizer estimates
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there are 140 million
men worldwide
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who have trouble
achieving erection.
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.
Understand that we're really dealing with
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a worldwide
medical problem.
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This has been of
interest to men,
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you know,
from time immemorial.
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.
As fast as pharmacists count them,
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men are buying them.
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.
After two weeks on pharmacy shelves,
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this little blue diamond
is the fastest selling
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prescription pill ever.
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.
A US internet provider can hardly keep up.
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In Saudi Arabia, men pay as
much as $100 for a single pill.
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But in Japan where
it's not approved yet,
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a travel agency offers four
day tours to Hawaii to get it.
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Airfare, hotel
and prescription
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all included.
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.
We're discussing the treatment of impotence
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and the use of Viagra.
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In Washington,
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we have former
presidential nominee,
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Bob Dole.
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.
I did not have sexual relations
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with that woman.
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I mean,
President Clinton's cock,
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Bob Dole's cock.
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Now you know you don't want
to hear about Bob Dole's cock,
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you know?
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* Huh? What? Right Uh
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* Huh? Right
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Viagra may wind up creating
a sexual revolution for men,
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but what about women?
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- Camera's rolling.
- Mark it.
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Alpha roll. Colour mark.
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.
Okay, so first question,
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can you tell me what you
learned in medical school
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about women's sexual health?
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So when I was a
medical student,
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we had
pretty robust
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sexual health
lectures,
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but mainly centred
around male sexual health.
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And I realized very quickly
the gaps that existed,
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including simple as,
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learning how to
examine a clitoris.
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So you learn
absolutely nothing
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in medical school
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about sexual
medicine
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at all for anybody.
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In fact, in the
OBGYN residency,
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the word clitoris
doesn't appear anywhere
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in what they have to learn.
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In fact, they tell you
don't touch the clitoris
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as to not make the
patient uncomfortable.
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Can you imagine me as a
urologist if I was taught
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don't touch the penis
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'cause you would make
the man uncomfortable?
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In my experience,
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unfortunately female
sexual health
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was all about
delivering babies,
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doing women's well visits,
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a little bit on
gynaecological cancers,
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but that's really it.
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And I went to Columbia.
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I mean, that's one of the best
medical schools in the country.
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What I didn't learn
about sexual medicine
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is pretty much
everything.
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The only memory I have
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of sexual medicine coming
up in medical school
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was this like
weird film they showed
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of like, hippies having sex.
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It was really cringey,
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and a lot of people just
like kind of walked out.
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.
We often will define sex
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really in
terms of
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how the male
engages in sex.
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Men get an erection,
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ejaculate, feel pleasure.
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But unfortunately, a much
larger number of women
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don't experience that.
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That's the orgasm gap.
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The orgasm gap is,
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it's maddening because in
order to have an orgasm,
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there are a number of
different parts of the vulva
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that need to be stimulated.
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The brain needs
to be stimulated.
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There's a lot of
pieces that go into it
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and people then suddenly
say it's complex
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and that it's unattainable.
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But when it comes to a penis,
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it's just assumed that if
that penis can't have an orgasm,
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there's a serious problem
with that individual.
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The gap starts
when we realize
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that society doesn't
really care whether or not
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someone with a
clitoris has an orgasm.
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And once you realize that,
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you recognize where all
these balls get dropped.
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.
No one is talking about pleasure and orgasms.
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No one is talking
about libido at all.
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It really doesn't
matter to our society
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whether people like
sex or don't like sex
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as long as they have
sex to make babies
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and we procreate as a society.
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And so we've ignored
it completely.
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* One thing on my mind
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.
When Viagra was approved in 1998,
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it was deemed to meet such an
important unmet medical need,
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it was literally fast
tracked for approval.
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It received the kind of
rare status we reserve
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for lifesaving cancer
drugs or rare diseases.
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So literally a
national emergency
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if men can't get it up.
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This is a subject you will
not see discussed much
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on television.
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Were you embarrassed?
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00:08:05,018 --> 00:08:06,419
Yeah, I was- still am.
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I mean, it's something you
don't run around, you know,
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00:08:08,021 --> 00:08:10,290
sit around talking
about in a coffee shop
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or particularly in a
public television program.
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I just really have to comment
on to Dr, uh, to Senator Dole.
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00:08:16,930 --> 00:08:18,999
What he just did was
just truly amazing to,
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00:08:19,032 --> 00:08:20,467
to discuss in-in public,
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00:08:20,500 --> 00:08:23,637
in a public forum what it's
like to have this problem.
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00:08:23,671 --> 00:08:24,738
The-the humiliation,
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00:08:24,772 --> 00:08:26,640
the embarrassment,
the frustration.
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My name is Irwin Goldstein
and, uh, I love sexual medicine.
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There are so many sufferers
with this condition.
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They stay in closets.
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They do not talk about this
and it's just wonderful.
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Okay, let me answer
your question.
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Impotence means
you're not a man.
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Being a male,
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00:08:43,757 --> 00:08:45,693
you're supposed to
have an erection,
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00:08:45,726 --> 00:08:47,494
uh, on demand.
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00:08:47,527 --> 00:08:50,964
So in the days prior
to the oral pill,
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00:08:50,998 --> 00:08:52,733
it was considered,
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00:08:52,800 --> 00:08:54,134
I don't want to
talk about it.
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00:08:54,167 --> 00:08:55,836
Divorce
happened commonly,
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00:08:55,869 --> 00:08:57,871
uh, depression happened.
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00:08:59,707 --> 00:09:03,343
.
Irwin Goldstein is the godfather of sexual medicine.
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00:09:03,376 --> 00:09:07,347
I mean, he was the key
investigator on the trial
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00:09:07,380 --> 00:09:08,849
that got Viagra approved.
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00:09:08,882 --> 00:09:13,621
Irwin really did something
spectacular, um, with Viagra.
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00:09:13,654 --> 00:09:16,256
And I think once he solved
that problem for men,
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00:09:16,323 --> 00:09:17,691
he said...
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00:09:17,891 --> 00:09:19,359
women.
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00:09:19,392 --> 00:09:21,361
.
May 14th, 1998,
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00:09:21,394 --> 00:09:22,730
a day I will never forget.
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00:09:22,763 --> 00:09:24,497
The New England
Journal of Medicine
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00:09:24,531 --> 00:09:27,668
published finally
all the data on Viagra.
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00:09:27,701 --> 00:09:29,402
I was the first author
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00:09:29,469 --> 00:09:30,704
and all the phone calls
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00:09:30,738 --> 00:09:33,406
from people who
had any concerns,
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00:09:33,440 --> 00:09:34,875
came to our office.
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00:09:34,908 --> 00:09:36,744
And guess what the gender was?
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00:09:38,278 --> 00:09:39,379
.
Hi Dr. Goldstein,
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00:09:39,412 --> 00:09:42,783
happily married lady
here for over ten years.
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00:09:42,850 --> 00:09:43,951
My husband's not the issue.
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00:09:44,017 --> 00:09:45,919
And we used to have
a great love life,
225
00:09:45,953 --> 00:09:48,055
but I just don't find myself
wanting to have sex.
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00:09:48,088 --> 00:09:49,222
.
Dr. Goldstein,
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00:09:49,256 --> 00:09:50,824
calling about this Viagra pill,
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00:09:50,858 --> 00:09:52,425
not for my boyfriend.
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00:09:52,459 --> 00:09:54,061
He's got no problem.
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00:09:54,361 --> 00:09:56,429
.
Congratulations on getting my husband a boner.
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00:09:56,463 --> 00:09:57,965
What do you have for me?
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00:09:58,031 --> 00:09:59,199
.
They're off the planet!
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00:09:59,232 --> 00:10:01,101
I don't know where they
think these men on Viagra
234
00:10:01,134 --> 00:10:03,136
are gonna stick all
those erections.
235
00:10:04,304 --> 00:10:06,874
.
I said, Hey, we're very busy.
236
00:10:06,907 --> 00:10:07,908
I'm a urologist.
237
00:10:07,941 --> 00:10:10,577
I do the men's sexual problems.
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00:10:10,610 --> 00:10:12,913
There's gynecologist,
they deal with women.
239
00:10:12,946 --> 00:10:15,683
And I said, "If you have any,
any issues, come back to me
240
00:10:15,716 --> 00:10:16,784
"and let me tell
you what's going.
241
00:10:16,850 --> 00:10:18,118
"You know, tell me
what's going on."
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00:10:18,151 --> 00:10:19,452
And to a T,
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00:10:19,486 --> 00:10:20,721
everyone called back.
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00:10:20,754 --> 00:10:22,422
"Gynecologists
aren't doing this.
245
00:10:22,455 --> 00:10:25,592
"The gynecologist said,
'Go see Dr. Goldstein.'"
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00:10:25,625 --> 00:10:27,294
So I was like, okay.
247
00:10:27,360 --> 00:10:30,998
I finally learn that we
need to take care of women
248
00:10:31,064 --> 00:10:32,800
with sexual health problems.
249
00:10:33,901 --> 00:10:36,436
.
I first learned about sexual medicine as a career
250
00:10:36,469 --> 00:10:37,938
when I was in medical school.
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00:10:37,971 --> 00:10:39,773
And realized
252
00:10:39,807 --> 00:10:41,641
that there was this whole
world of information
253
00:10:41,675 --> 00:10:44,845
that I did not know even
existed about sexual health,
254
00:10:44,912 --> 00:10:48,615
about pain,
about orgasm, arousal,
255
00:10:48,648 --> 00:10:52,285
and realized I wanted it to
be a part of my practice.
256
00:10:52,319 --> 00:10:53,286
Women's sexual health,
257
00:10:53,320 --> 00:10:54,254
and vulvas in general,
258
00:10:54,287 --> 00:10:57,124
have never been a
priority of our society.
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00:10:57,157 --> 00:11:00,360
We can see that as deep
as the terminology used
260
00:11:00,427 --> 00:11:02,462
for the innervation
of the vulva.
261
00:11:02,495 --> 00:11:03,630
The pudendal nerve
262
00:11:03,663 --> 00:11:06,834
is the nerve that provides
most of the sensation,
263
00:11:06,900 --> 00:11:08,936
particularly in regards
to sexual function,
264
00:11:08,969 --> 00:11:10,470
to the vulva, the clitoris,
265
00:11:10,503 --> 00:11:12,672
the labia, the vestibule.
266
00:11:12,740 --> 00:11:15,976
And pudendal literally
means "shame."
267
00:11:16,009 --> 00:11:18,812
Often patients don't feel
like they deserve sex,
268
00:11:18,846 --> 00:11:19,980
they don't deserve intimacy,
269
00:11:20,013 --> 00:11:22,282
they don't deserve
pleasure or connection.
270
00:11:22,315 --> 00:11:24,617
And when that is lost,
271
00:11:24,651 --> 00:11:28,355
I think that a piece of
them is really broken.
272
00:11:28,421 --> 00:11:29,356
More often
than not,
273
00:11:29,422 --> 00:11:30,690
women will
just say,
274
00:11:30,758 --> 00:11:32,192
"Oh yeah, I,
you know,
275
00:11:32,225 --> 00:11:33,660
"I haven't
orgasmed in years,
276
00:11:33,693 --> 00:11:34,895
"but it's fine, whatever.
277
00:11:34,962 --> 00:11:35,829
"I mean, I just gave up."
278
00:11:35,863 --> 00:11:37,530
Not that it's someone
who's like okay
279
00:11:37,564 --> 00:11:38,899
with not having
sexual pleasure,
280
00:11:38,966 --> 00:11:41,168
it's just that they didn't
think that they deserved it.
281
00:11:41,201 --> 00:11:45,705
And a lot of my job is
actually normalizing
282
00:11:45,739 --> 00:11:48,075
that it's okay to want
more for yourself
283
00:11:48,141 --> 00:11:49,910
when it comes to sexual
pleasure and desire,
284
00:11:49,977 --> 00:11:54,181
which is very different than
society's approach to men,
285
00:11:54,214 --> 00:11:55,749
where it is a right.
286
00:11:56,583 --> 00:11:58,185
Your genitalia affects
287
00:11:58,218 --> 00:11:59,853
how you're treated in
the healthcare system.
288
00:11:59,887 --> 00:12:01,889
You know, I trained
as a urologist
289
00:12:01,922 --> 00:12:06,226
and I was very used
to objective data,
290
00:12:06,259 --> 00:12:07,360
and objective evidence,
291
00:12:07,394 --> 00:12:09,830
and really listening
to our patients.
292
00:12:09,863 --> 00:12:10,898
And I didn't realize
293
00:12:10,931 --> 00:12:14,001
that was something very
unique to the fact that
294
00:12:14,034 --> 00:12:16,469
I was working with
predominantly men,
295
00:12:16,503 --> 00:12:19,572
'cause when I started working
in the women's health space,
296
00:12:19,606 --> 00:12:23,243
I was oftentimes
listening to my patients
297
00:12:23,276 --> 00:12:26,213
telling me the consistent
medical gaslighting
298
00:12:26,246 --> 00:12:27,247
that they were experiencing
299
00:12:27,314 --> 00:12:29,749
when it came to their vulva,
vaginal healthcare.
300
00:12:29,817 --> 00:12:31,952
A lot of times when
people come in with problems
301
00:12:32,019 --> 00:12:35,088
and are previously told,
"It's all in your head,"
302
00:12:35,155 --> 00:12:37,224
okay, basically getting
medically gaslit,
303
00:12:37,257 --> 00:12:39,426
the default sometimes
is to blame the patient
304
00:12:39,492 --> 00:12:42,729
when you as the provider
don't know how to help them.
305
00:12:42,762 --> 00:12:44,264
Uh, your name, uh,
is Mrs. Martin,
306
00:12:44,297 --> 00:12:45,265
is that right?
307
00:12:45,298 --> 00:12:46,566
That's correct.
308
00:12:46,599 --> 00:12:48,468
.
Well try and tell me for starters if you can,
309
00:12:48,535 --> 00:12:50,570
what is the current dilemma?
310
00:12:50,603 --> 00:12:52,405
What's going on that troubles?
311
00:12:52,439 --> 00:12:53,706
.
The idea of it's all in your head
312
00:12:53,740 --> 00:12:55,843
is a tale as old as time.
313
00:12:55,876 --> 00:12:58,078
"Have a date night,
drink a glass of wine,
314
00:12:58,111 --> 00:12:59,913
"read Fifty Shades of Grey.
315
00:12:59,947 --> 00:13:02,049
"Here's a good therapist,
go to this therapist.
316
00:13:02,082 --> 00:13:03,416
"It's all trauma."
317
00:13:03,450 --> 00:13:08,455
Well, I-I don't have
climaxes anymore at all.
318
00:13:08,488 --> 00:13:10,090
And I feel like I'm
just submitting now,
319
00:13:10,123 --> 00:13:12,926
that I'm not, I'm not giving
anything or getting anything.
320
00:13:12,960 --> 00:13:14,127
.
In general,
321
00:13:14,194 --> 00:13:17,064
people don't like talking
about sexual problems.
322
00:13:17,097 --> 00:13:21,835
Um, most providers don't
do sexual medicine.
323
00:13:21,902 --> 00:13:24,804
Have you ever been to a doctor
who does sexual medicine?
324
00:13:24,838 --> 00:13:25,906
There's so few of them.
325
00:13:25,939 --> 00:13:27,975
Your sexual experiences,
326
00:13:28,008 --> 00:13:29,476
which are very
important to you,
327
00:13:29,542 --> 00:13:32,245
you're not willing to share and
they're not willing to hear,
328
00:13:32,279 --> 00:13:34,281
but they should be.
329
00:13:34,314 --> 00:13:36,016
They should be as,
330
00:13:36,083 --> 00:13:39,119
if they're bothering you
and it's affecting your,
331
00:13:39,152 --> 00:13:43,423
your yourself, your, your, your
relationship with someone else,
332
00:13:43,456 --> 00:13:44,824
your ability to be a parent,
333
00:13:44,892 --> 00:13:47,494
your ability to be a
good worker at work,
334
00:13:47,527 --> 00:13:49,963
uh, you should have the
opportunity to discuss this.
335
00:13:50,663 --> 00:13:54,001
.
Irwin Goldstein is a mad scientist
336
00:13:54,067 --> 00:13:56,103
who loves discovery
337
00:13:56,136 --> 00:14:00,807
and does it for the
care of his patients
338
00:14:00,840 --> 00:14:02,342
through and through.
339
00:14:04,677 --> 00:14:06,846
.
I'll take you back to 2010.
340
00:14:06,914 --> 00:14:08,115
I'm in Miami
341
00:14:08,148 --> 00:14:10,984
at the Sexual Medicine
Society Conference,
342
00:14:11,018 --> 00:14:13,586
and it's the best researchers
in the world on sex.
343
00:14:15,155 --> 00:14:17,925
So here's Irwin chasing
me around with his MacBook
344
00:14:17,958 --> 00:14:19,893
and he said, "You
have to watch these,
345
00:14:19,960 --> 00:14:22,495
"you have to watch these,
you have to watch these."
346
00:14:22,529 --> 00:14:25,999
So today is 10 21 10.
347
00:14:26,033 --> 00:14:28,201
It's, uh, Thursday.
348
00:14:29,269 --> 00:14:31,538
There was a drug
company in Germany
349
00:14:31,571 --> 00:14:36,176
that was studying an
alternative drug for depression.
350
00:14:36,209 --> 00:14:38,545
And of course,
just like Viagra,
351
00:14:38,578 --> 00:14:40,480
it was found to be
amazingly successful
352
00:14:40,513 --> 00:14:44,717
in helping women who had
low libido or low desire.
353
00:14:44,751 --> 00:14:48,021
We have patient 24163
354
00:14:48,055 --> 00:14:49,889
of the flibanserin
open label trial.
355
00:14:49,957 --> 00:14:51,558
I had patients on this.
356
00:14:51,624 --> 00:14:54,094
I filmed them saying,
"Oh my God,
357
00:14:54,161 --> 00:14:57,064
"after taking flibanserin
I'm smiling and I'm happy
358
00:14:57,130 --> 00:15:00,167
"and I stare at my partner and
I just want to be with them."
359
00:15:00,200 --> 00:15:01,401
And why we're filming this?
360
00:15:01,434 --> 00:15:03,070
This is really cool,
her results.
361
00:15:03,103 --> 00:15:07,407
So I'm gonna turn this
around and patient 24163.
362
00:15:07,440 --> 00:15:08,408
How are ya?
363
00:15:08,441 --> 00:15:09,742
I'm fine.
364
00:15:09,776 --> 00:15:11,878
.
So this is a little weird, but you know, I, you know,
365
00:15:11,911 --> 00:15:13,213
this is your really
last chance to,
366
00:15:13,246 --> 00:15:15,415
to document this to humanity.
367
00:15:15,448 --> 00:15:19,186
So you're on, tell us
side effects, benefits.
368
00:15:19,219 --> 00:15:20,587
How did you do
with this drug?
369
00:15:20,653 --> 00:15:23,223
I did phenomenal
on this drug.
370
00:15:23,256 --> 00:15:24,992
I feel like a new
woman on this drug.
371
00:15:27,294 --> 00:15:28,595
.
At that conference,
372
00:15:28,628 --> 00:15:31,131
this company presented
this brain scan imaging
373
00:15:31,198 --> 00:15:33,000
of a women struggling
with their libido.
374
00:15:34,067 --> 00:15:38,071
And it was like
lightning struck!
375
00:15:38,105 --> 00:15:39,139
Holy shit!
376
00:15:39,206 --> 00:15:41,241
It's biology!
377
00:15:45,212 --> 00:15:48,781
.
HSDD or Hypoactive Sexual Desire Disorder
378
00:15:48,848 --> 00:15:50,050
is the name.
379
00:15:50,083 --> 00:15:53,886
It was first characterized
in the literature in 1977.
380
00:15:53,920 --> 00:15:57,057
And it basically is this like
absence of spontaneous thoughts
381
00:15:57,090 --> 00:15:59,059
or interest.
382
00:15:59,092 --> 00:16:01,995
And we realize it's in the
sex centre of the brain.
383
00:16:03,663 --> 00:16:06,466
You know, we're
hardwired to procreate
384
00:16:06,499 --> 00:16:09,069
and for, you know,
millions of people,
385
00:16:09,102 --> 00:16:11,171
something goes off
kilter in that wiring.
386
00:16:12,005 --> 00:16:14,241
I had no sexual desire.
387
00:16:14,274 --> 00:16:16,309
Libido was almost zero.
388
00:16:16,376 --> 00:16:18,278
.
It was such a common thread.
389
00:16:18,311 --> 00:16:22,182
And, you know, what happened
is I saw those videos,
390
00:16:22,249 --> 00:16:25,285
I completely saw myself
in those videos.
391
00:16:26,386 --> 00:16:27,954
I was in a place
in a relationship
392
00:16:27,987 --> 00:16:29,789
where I was
deeply disconnected.
393
00:16:31,124 --> 00:16:33,360
I was in the
exact same place,
394
00:16:33,426 --> 00:16:35,428
really struggling
with this issue.
395
00:16:37,264 --> 00:16:38,831
I just never think about it,
396
00:16:38,898 --> 00:16:40,367
like it's gone.
397
00:16:40,433 --> 00:16:42,469
It used to be there,
but it's gone.
398
00:16:43,336 --> 00:16:45,805
Go talk to hundreds of women
399
00:16:45,838 --> 00:16:49,176
who have nothing in common
other than this one issue,
400
00:16:49,242 --> 00:16:53,012
and listen to them all give
you the exact same words:
401
00:16:53,046 --> 00:16:54,181
It's gone.
402
00:16:54,247 --> 00:16:56,983
And they had been
conditioned to not even
403
00:16:57,016 --> 00:16:58,051
sort of fight for it
404
00:16:58,118 --> 00:17:01,688
because, well, your
pleasure doesn't matter.
405
00:17:01,721 --> 00:17:03,223
"Just go along.
406
00:17:03,290 --> 00:17:04,224
"This is what it is.
407
00:17:04,291 --> 00:17:05,858
"Relax, honey, have a bath.
408
00:17:05,892 --> 00:17:06,926
"Schedule date night.
409
00:17:06,959 --> 00:17:08,161
"Buy sexier lingerie.
410
00:17:08,195 --> 00:17:09,529
"Do better."
411
00:17:09,562 --> 00:17:11,164
You do better.
412
00:17:11,198 --> 00:17:12,332
Fuck you.
413
00:17:15,868 --> 00:17:17,504
.
I had never talked about libido.
414
00:17:18,705 --> 00:17:21,074
I think that's another
thing where I thought,
415
00:17:21,141 --> 00:17:23,676
after you have a kid that
goes away, you know?
416
00:17:23,710 --> 00:17:26,146
That was kind of
the narrative from
417
00:17:26,179 --> 00:17:27,747
my elders, right?
418
00:17:27,814 --> 00:17:28,881
And the women
around me,
419
00:17:28,948 --> 00:17:30,517
that you're a mother now
420
00:17:30,550 --> 00:17:33,186
and you focus on these
things and that's behind you.
421
00:17:33,220 --> 00:17:35,922
So no discussion about it.
422
00:17:38,591 --> 00:17:43,230
.
I went from a scale of one to ten on the libido,
423
00:17:43,263 --> 00:17:45,498
I was eleven.
424
00:17:45,532 --> 00:17:48,368
Uh, and then when
menopause hit,
425
00:17:48,401 --> 00:17:51,171
I became
a negative three.
426
00:17:52,139 --> 00:17:54,174
Um, it was devastating.
427
00:17:54,207 --> 00:17:59,346
As a woman, we, we
love to feel desirable
428
00:17:59,379 --> 00:18:01,080
and happy with
their relationships
429
00:18:01,148 --> 00:18:02,915
and things like that.
430
00:18:02,949 --> 00:18:03,916
And for me,
431
00:18:03,950 --> 00:18:06,886
I felt like someone
had just slayed me.
432
00:18:06,919 --> 00:18:12,058
I, I tell people I, I lost
touch with my inner goddess.
433
00:18:14,294 --> 00:18:17,164
.
My husband likes to practice what he preaches.
434
00:18:17,197 --> 00:18:19,532
And one day he came home
from work and he said,
435
00:18:19,566 --> 00:18:22,435
we've just developed
a new questionnaire.
436
00:18:22,502 --> 00:18:24,237
It was basically the
beginning of testing
437
00:18:24,271 --> 00:18:26,273
for Addyi.
438
00:18:26,306 --> 00:18:28,275
And he says, just take
the test for fun.
439
00:18:28,308 --> 00:18:31,544
And I took it and he
goes, holy, you've got HSD!
440
00:18:32,412 --> 00:18:34,914
When you have Hypoactive
Sexual Desire Disorder,
441
00:18:34,947 --> 00:18:36,249
which is what I had,
442
00:18:36,283 --> 00:18:37,817
you're not aware that
it's in your cognition.
443
00:18:37,884 --> 00:18:39,386
Well, everybody has
it differently.
444
00:18:39,419 --> 00:18:40,787
It may mean that, you know,
445
00:18:40,820 --> 00:18:42,389
when your partner
walks through the door,
446
00:18:42,422 --> 00:18:44,824
you used to wanna jump
his bones or her bones
447
00:18:44,891 --> 00:18:46,426
and that's not of
interest anymore.
448
00:18:46,459 --> 00:18:48,828
It may be that while
you're in bed having sex,
449
00:18:48,895 --> 00:18:49,896
you're thinking about, ugh,
450
00:18:49,929 --> 00:18:51,231
I have to put the
wash in the dryer,
451
00:18:51,264 --> 00:18:53,633
I have to buy milk for the
kids before school tomorrow.
452
00:18:53,666 --> 00:18:55,602
Or it may be that you don't
want your partner to touch you
453
00:18:55,635 --> 00:18:56,769
because you have,
454
00:18:56,803 --> 00:18:58,305
you've developed,
you know, aversion.
455
00:18:58,371 --> 00:18:59,839
It couldn't mean
a lot of things.
456
00:18:59,906 --> 00:19:03,109
But for me, I was having
essentially duty sex.
457
00:19:03,142 --> 00:19:05,512
When I had sex, it was good,
458
00:19:05,578 --> 00:19:08,415
but I had no reason to
want to have sex again.
459
00:19:11,484 --> 00:19:14,821
.
I met my husband at a party at his uncle's house
460
00:19:17,424 --> 00:19:22,329
and in our early relationship
there was no problem
461
00:19:22,362 --> 00:19:25,765
with desire with sex.
462
00:19:25,798 --> 00:19:27,800
One time there was a
construction site
463
00:19:27,834 --> 00:19:29,802
and we decided that
464
00:19:29,836 --> 00:19:32,405
this would be a
great opportunity.
465
00:19:32,439 --> 00:19:35,007
I mean, it was just spur of
the moment all the time.
466
00:19:35,041 --> 00:19:37,644
Spur of the moment,
just boom, we're ready to go.
467
00:19:37,677 --> 00:19:41,448
Um, and then we had children
468
00:19:41,481 --> 00:19:45,084
and there was absolutely
no problem whatsoever.
469
00:19:45,117 --> 00:19:46,152
And then all of a sudden,
470
00:19:46,185 --> 00:19:48,888
it was like somebody
pulled the plug.
471
00:19:48,955 --> 00:19:50,523
I had zero desire.
472
00:19:52,425 --> 00:19:53,660
.
When I first met her I,
473
00:19:53,693 --> 00:19:57,497
I thought she was a,
a real hottie.
474
00:19:57,530 --> 00:20:00,032
No, we were a
young, healthy,
475
00:20:00,066 --> 00:20:01,434
- sexually active-
- Amorous.
476
00:20:01,468 --> 00:20:04,471
Couple. Yeah,
and, uh, yeah,
477
00:20:04,504 --> 00:20:07,307
and it, it was, it was
good for a long time.
478
00:20:07,340 --> 00:20:11,043
When it became evident
that she wasn't responding,
479
00:20:11,110 --> 00:20:13,413
I almost got angry.
480
00:20:13,480 --> 00:20:14,547
Is she mad at me
about something?
481
00:20:14,614 --> 00:20:16,148
Did I do something?
482
00:20:16,182 --> 00:20:17,717
Uh, does she think
I'm cheating?
483
00:20:17,750 --> 00:20:18,718
I never did.
484
00:20:18,751 --> 00:20:20,820
Never have, never will.
485
00:20:20,853 --> 00:20:25,925
Um, so yeah, it was tough.
486
00:20:25,992 --> 00:20:27,360
.
So that's why I decided
487
00:20:27,394 --> 00:20:29,596
that when I heard of
this clinical trial,
488
00:20:29,662 --> 00:20:32,365
I would definitely
give that a try.
489
00:20:32,399 --> 00:20:36,836
And oh my gosh,
it was just amazing.
490
00:20:36,869 --> 00:20:38,571
Your whole
relationship with your,
491
00:20:38,638 --> 00:20:40,340
or at least mine
with my husband,
492
00:20:40,373 --> 00:20:43,410
was stressed or strained.
493
00:20:43,476 --> 00:20:44,577
.
And on the medication?
494
00:20:44,611 --> 00:20:48,715
On the medication
I chase him.
495
00:20:48,748 --> 00:20:49,749
.
Awesome.
496
00:20:49,782 --> 00:20:52,452
It is, it is unbelievable.
497
00:20:52,519 --> 00:20:55,388
I love my husband
tremendously,
498
00:20:55,422 --> 00:20:58,891
but with this drug I
love him even more.
499
00:20:58,925 --> 00:21:02,261
And our, our sexual
experiences were,
500
00:21:02,295 --> 00:21:04,230
were incredible.
501
00:21:04,263 --> 00:21:06,599
It was, it was like
I was a new woman.
502
00:21:10,437 --> 00:21:14,273
.
Will the FDA approve the so-called female Viagra?
503
00:21:14,341 --> 00:21:16,709
A drug for women with
unhappy sex lives.
504
00:21:16,743 --> 00:21:18,745
I'm at the FDA
meeting right now.
505
00:21:18,778 --> 00:21:20,647
I'll have more in this hour.
506
00:21:20,713 --> 00:21:24,384
Boehringer Ingelheim be
applied for approval by the FDA.
507
00:21:24,417 --> 00:21:26,285
Today's agenda involves
discussion related
508
00:21:26,319 --> 00:21:27,454
to new drug application.
509
00:21:27,520 --> 00:21:31,891
NDA 22526 Flibanserin
hundred milligrams tablets.
510
00:21:31,924 --> 00:21:33,460
Because I was doing
a lot of work
511
00:21:33,526 --> 00:21:36,929
with antidepressant associated
sexual dysfunction,
512
00:21:36,963 --> 00:21:39,432
I was an advisor.
513
00:21:39,466 --> 00:21:42,735
I appreciate the opportunity to
be able to speak with you today.
514
00:21:42,769 --> 00:21:45,171
For male
erectile dysfunction,
515
00:21:45,237 --> 00:21:47,273
and what they had
used a measure,
516
00:21:47,306 --> 00:21:51,478
was this sexual event
successful for you?
517
00:21:51,511 --> 00:21:55,448
Meaning the penis was rigid
enough to penetrate a vagina.
518
00:21:55,482 --> 00:21:58,150
They decided to try to
apply that to women.
519
00:21:58,184 --> 00:21:59,151
And we said,
520
00:21:59,185 --> 00:22:02,288
what is a successful
sexual event in women?
521
00:22:02,321 --> 00:22:04,824
Do you think that it
might be having an orgasm
522
00:22:04,857 --> 00:22:07,293
'cause that's really
not related to desire.
523
00:22:07,326 --> 00:22:10,663
And that was the
sort of first real foray
524
00:22:10,697 --> 00:22:16,302
into them not really
understanding women's sexuality.
525
00:22:16,335 --> 00:22:17,937
These are the numbers
that you see,
526
00:22:17,970 --> 00:22:20,707
so these are women
who have HSDD.
527
00:22:20,773 --> 00:22:23,510
They do not have depression.
528
00:22:23,543 --> 00:22:27,547
You can see that HSDD
is the most common
529
00:22:27,614 --> 00:22:29,816
sexual dysfunction
530
00:22:29,849 --> 00:22:34,153
as compared to effects
on arousal or orgasm.
531
00:22:34,186 --> 00:22:36,022
The studies were positive
532
00:22:36,055 --> 00:22:40,326
and it showed that people's
sexual functioning improved
533
00:22:40,359 --> 00:22:42,495
over time when they
were on this drug.
534
00:22:42,529 --> 00:22:47,534
But ultimately Boehringer
Ingelheim had it turned down
535
00:22:47,567 --> 00:22:49,436
for approval by the FDA.
536
00:22:51,504 --> 00:22:53,806
.
At that meeting in Miami,
537
00:22:53,840 --> 00:22:57,844
the German company went to all
the researchers in the world
538
00:22:57,877 --> 00:23:00,312
and said, we're not
gonna develop it.
539
00:23:01,681 --> 00:23:04,517
And you could feel the
air leave the room.
540
00:23:04,551 --> 00:23:09,556
.
I am so, so upset that this is terminating
541
00:23:09,589 --> 00:23:15,027
because this Flibanserin
can change people's lives,
542
00:23:15,061 --> 00:23:16,563
they can change relationships,
543
00:23:16,596 --> 00:23:20,900
they can, um, make a
person whole again.
544
00:23:20,933 --> 00:23:24,437
And she is patient 24174.
545
00:23:24,471 --> 00:23:25,772
And she, uh,
546
00:23:25,838 --> 00:23:29,241
because closed up,
we had to close out the trial.
547
00:23:29,275 --> 00:23:31,277
.
What was surprising is that a company
548
00:23:31,343 --> 00:23:34,481
that had found this kind
of spectacular discovery
549
00:23:34,547 --> 00:23:36,583
was not going to pursue it
550
00:23:36,616 --> 00:23:39,118
'cause they didn't want to
take on women and sex, right?
551
00:23:39,185 --> 00:23:40,219
No thank you,
552
00:23:40,252 --> 00:23:41,921
we're not getting
into this debate.
553
00:23:41,954 --> 00:23:44,256
And I think Irwin
knew that too,
554
00:23:44,290 --> 00:23:46,759
which is why he said you need
to do something about this.
555
00:23:46,793 --> 00:23:50,797
The science was there,
it required a champion.
556
00:23:50,863 --> 00:23:53,099
I said, please just
get on an airplane,
557
00:23:53,132 --> 00:23:54,233
fly to this place.
558
00:23:54,266 --> 00:23:56,636
For one dollar they'll probably
give you the medicine.
559
00:23:56,669 --> 00:23:58,605
I sort of almost begged.
560
00:23:58,638 --> 00:24:00,306
I mean, you have to develop it.
561
00:24:00,372 --> 00:24:02,408
Irwin chose me,
it spoke to me,
562
00:24:02,441 --> 00:24:03,876
this is what I was
struggling with
563
00:24:03,910 --> 00:24:06,646
and I was gonna fight
for what I deserved
564
00:24:06,679 --> 00:24:08,581
and I was determined.
565
00:24:08,615 --> 00:24:10,449
And so I bought the drug.
566
00:24:12,451 --> 00:24:14,320
* Gimme what I want,
what I want, what I want *
567
00:24:14,386 --> 00:24:15,822
* want, want, want,
what I want *
568
00:24:15,855 --> 00:24:17,957
.
And so, what do you do when you get a drug through the FDA?
569
00:24:17,990 --> 00:24:19,492
You sit down with the FDA
570
00:24:19,526 --> 00:24:22,361
and you say, okay,
here's this product,
571
00:24:22,428 --> 00:24:23,462
what is the roadmap?
572
00:24:23,496 --> 00:24:24,797
* Gimme what I want,
what I want, what I want
573
00:24:24,831 --> 00:24:25,865
* what I want, what I want
574
00:24:25,932 --> 00:24:27,133
* Like a Spice Girl *
575
00:24:27,166 --> 00:24:28,835
.
They tell you what endpoints you have to meet
576
00:24:28,868 --> 00:24:29,869
in clinical trials.
577
00:24:29,936 --> 00:24:31,638
They define success for you
578
00:24:31,671 --> 00:24:34,507
and you have to prove it with
statistical significance.
579
00:24:35,374 --> 00:24:38,177
So that's what we really
spent our first year doing
580
00:24:38,210 --> 00:24:40,647
is all the things that
the FDA had asked of us,
581
00:24:40,680 --> 00:24:41,814
good stewards of science,
582
00:24:41,848 --> 00:24:44,383
we went out,
we did all that work.
583
00:24:44,450 --> 00:24:47,186
And I remember being
just so excited.
584
00:24:47,219 --> 00:24:48,821
Like we've done it,
we did it,
585
00:24:48,855 --> 00:24:50,022
it works!
586
00:24:50,056 --> 00:24:54,661
This drug was about women
living life on their own terms,
587
00:24:54,694 --> 00:24:57,564
so I wanted a woman's name.
588
00:24:57,630 --> 00:25:01,167
A character that I loved
was actually Addison
589
00:25:01,200 --> 00:25:02,669
on Grey's Anatomy.
590
00:25:02,702 --> 00:25:05,371
I like that she lives
life on her own terms,
591
00:25:05,404 --> 00:25:07,239
so we called it Addyi.
592
00:25:14,213 --> 00:25:16,382
Our very first
meeting with the FDA,
593
00:25:16,415 --> 00:25:18,685
there was a tension
in that room.
594
00:25:18,718 --> 00:25:22,822
You can imagine you walk in
like company sits on one side,
595
00:25:22,855 --> 00:25:24,857
FDA sits on the other side,
596
00:25:24,891 --> 00:25:26,726
it's like a face off.
597
00:25:26,793 --> 00:25:30,730
And there was just this sense
598
00:25:30,763 --> 00:25:34,734
that this was not gonna be a
straightforward conversation.
599
00:25:35,668 --> 00:25:37,837
Here I am running a company,
600
00:25:37,870 --> 00:25:39,606
totally a woman
in a man's world.
601
00:25:41,340 --> 00:25:45,578
When I left college I worked for
Fortune's most admired company,
602
00:25:45,645 --> 00:25:49,749
but I left Big Pharma because
it wasn't the fit for me.
603
00:25:49,816 --> 00:25:53,753
And I found this incredible
testosterone product for men
604
00:25:53,820 --> 00:25:56,756
and built my first business
out of that called Slate.
605
00:25:56,823 --> 00:26:00,760
And so, I had brought a
product to market for men
606
00:26:00,793 --> 00:26:02,094
that was FDA approved.
607
00:26:02,128 --> 00:26:03,896
So when all the
questions were different
608
00:26:03,930 --> 00:26:05,732
on a product for women,
609
00:26:05,765 --> 00:26:08,234
I knew something was up.
610
00:26:08,267 --> 00:26:09,869
And I asked this question,
611
00:26:09,902 --> 00:26:11,270
why are we being reviewed
612
00:26:11,303 --> 00:26:14,440
by the urology division
of the FDA
613
00:26:14,473 --> 00:26:18,745
when this is a drug that
works on neurotransmitters?
614
00:26:18,778 --> 00:26:19,746
And the answer was,
615
00:26:19,779 --> 00:26:22,514
"We review all the sex drugs."
616
00:26:22,548 --> 00:26:25,251
I said, "Yeah because
they've all been for men."
617
00:26:25,284 --> 00:26:28,087
And that was it,
like I stepped in it.
618
00:26:28,120 --> 00:26:29,789
I knew it as soon
as I said it,
619
00:26:29,856 --> 00:26:32,324
I could feel that
tension in the room,
620
00:26:32,391 --> 00:26:33,760
like how dare you,
621
00:26:33,793 --> 00:26:38,064
we are the experts on sex,
and yet they weren't.
622
00:26:38,097 --> 00:26:41,567
I walked out of that
meeting and I thought,
623
00:26:41,600 --> 00:26:43,803
science cures bias, right?
624
00:26:43,870 --> 00:26:46,138
Science always
knows the answer.
625
00:26:46,172 --> 00:26:49,008
I knew we'd actually
achieved all the results
626
00:26:49,075 --> 00:26:50,777
that they'd asked
us to achieve.
627
00:26:50,810 --> 00:26:53,445
And so, I was getting
ready to launch,
628
00:26:53,479 --> 00:26:55,247
and I had been in New York
629
00:26:55,281 --> 00:26:57,784
and I flew back to
Raleigh where I'm based.
630
00:26:58,617 --> 00:27:00,619
The whole company
is like waiting
631
00:27:00,653 --> 00:27:02,221
with the champagne chilling.
632
00:27:03,923 --> 00:27:06,926
The minute the plane landed,
my phone's blowing up.
633
00:27:06,959 --> 00:27:08,795
I got a call from my assistant.
634
00:27:08,828 --> 00:27:11,463
She's like, Hey, we
heard from the FDA,
635
00:27:11,497 --> 00:27:14,166
they came back and said no.
636
00:27:14,200 --> 00:27:17,169
And it was just like, pow!
637
00:27:17,203 --> 00:27:19,638
I thought, oh my God.
638
00:27:19,672 --> 00:27:22,041
I didn't know what
I was gonna say.
639
00:27:22,108 --> 00:27:23,810
My board knew
this was the day,
640
00:27:23,843 --> 00:27:25,812
my shareholders
knew this was the day,
641
00:27:25,845 --> 00:27:27,714
the patients knew
this was the day,
642
00:27:27,780 --> 00:27:29,816
Irwin knew this was the day.
643
00:27:30,717 --> 00:27:32,752
I'm like, gotta go in,
gotta face the music.
644
00:27:35,554 --> 00:27:38,324
I got everybody around
the table and I said,
645
00:27:38,357 --> 00:27:41,694
"We just heard from the FDA
and we were turned down."
646
00:27:41,728 --> 00:27:43,763
And it was silence.
647
00:27:47,233 --> 00:27:51,170
I remember sitting in the office
until the last person left.
648
00:27:51,203 --> 00:27:53,873
I was looking out the window
until I started to cry
649
00:27:54,974 --> 00:27:57,176
and I'm like, what the
hell are you doing?
650
00:27:57,209 --> 00:28:00,980
Like pick yourself back up,
we're going back into battle.
651
00:28:01,013 --> 00:28:05,251
And I thought not on my
fucking watch, no way.
652
00:28:06,185 --> 00:28:08,888
It was time to take 'em on.
653
00:28:10,122 --> 00:28:11,390
.
Viagra for women.
654
00:28:11,423 --> 00:28:12,591
It's a little pink pill
655
00:28:12,658 --> 00:28:14,861
that's supposed to
increase a woman's desire.
656
00:28:14,894 --> 00:28:18,164
And the FDA has already
said no to the drug.
657
00:28:18,197 --> 00:28:20,432
But the company is
appealing that decision.
658
00:28:22,401 --> 00:28:24,370
.
I had never heard of HSDD.
659
00:28:24,403 --> 00:28:26,405
I had never heard
of Flibanserin.
660
00:28:26,438 --> 00:28:28,707
There was a meeting
on my calendar, um,
661
00:28:28,741 --> 00:28:30,576
to meet with a
company called Sprout
662
00:28:30,609 --> 00:28:32,011
who was coming
to us for help.
663
00:28:32,044 --> 00:28:34,046
And so I went to the meeting
664
00:28:34,080 --> 00:28:35,915
and I met Cindy
who was a very,
665
00:28:35,948 --> 00:28:37,784
very different from
most of my clients.
666
00:28:39,251 --> 00:28:42,755
Ooh, what's coming?
667
00:28:42,822 --> 00:28:43,790
Hey, hey, hey.
668
00:28:43,856 --> 00:28:46,392
I remember that first meeting,
you know,
669
00:28:46,425 --> 00:28:49,728
this spectacular woman
came into the room.
670
00:28:49,762 --> 00:28:51,630
I was watching
her body language
671
00:28:51,697 --> 00:28:54,867
and I thought,
I think this is my soulmate.
672
00:28:54,901 --> 00:28:55,768
Theodore, I can't
believe you're not even
673
00:28:55,835 --> 00:28:57,669
paying attention, buddy.
674
00:28:58,437 --> 00:29:00,572
The plan is to make a plan.
675
00:29:00,606 --> 00:29:02,909
So how do you take
on the government
676
00:29:02,942 --> 00:29:05,577
for women's sexual pleasure?
677
00:29:05,611 --> 00:29:07,379
I was working
primarily in oncology,
678
00:29:07,413 --> 00:29:09,949
so trying to get cancer
drugs through the FDA,
679
00:29:10,016 --> 00:29:13,219
and I hadn't done much in the
reproductive health space.
680
00:29:13,252 --> 00:29:15,888
And Cindy walked in
with so much energy
681
00:29:15,922 --> 00:29:18,925
and started telling me
about HSDD and Flibanserin
682
00:29:18,958 --> 00:29:21,994
and the challenges that
FDA had given them.
683
00:29:22,061 --> 00:29:25,798
My first reaction honestly
in that moment was, oh these,
684
00:29:25,832 --> 00:29:28,134
these seem like great people
and an energized team,
685
00:29:28,200 --> 00:29:30,269
but I don't think I'm
gonna be able to help them.
686
00:29:34,173 --> 00:29:36,275
I didn't understand
the condition.
687
00:29:36,308 --> 00:29:38,978
You know, I thought of
it's, it's a sex drug,
688
00:29:39,011 --> 00:29:41,981
that sounds like something
that's not necessary.
689
00:29:42,014 --> 00:29:44,650
Oncology drugs are
saving people's lives
690
00:29:44,683 --> 00:29:47,186
and I didn't think
it was as important.
691
00:29:49,255 --> 00:29:54,060
The reason I decided to take
the case was Cindy showed me
692
00:29:54,093 --> 00:29:55,794
some real documented evidence
693
00:29:55,828 --> 00:29:58,130
of things FDA was
saying and asking for
694
00:29:58,164 --> 00:30:02,301
that pointed out to me
that FDA had a real bias
695
00:30:02,334 --> 00:30:06,839
rooted in maybe hangups
about women and sex and,
696
00:30:06,873 --> 00:30:09,208
and that FDA wasn't
thinking about this, um,
697
00:30:09,275 --> 00:30:10,943
in a truly scientific way.
698
00:30:10,977 --> 00:30:13,579
And I decided to take
it because as a lawyer
699
00:30:13,612 --> 00:30:16,448
it sort of rubbed my fairness
button the wrong way.
700
00:30:17,516 --> 00:30:22,054
.
When the drug first went up for FDA review in 2010,
701
00:30:22,121 --> 00:30:25,657
the FDA did not feel
that there was enough data
702
00:30:25,691 --> 00:30:28,460
to support its effectiveness.
703
00:30:28,494 --> 00:30:31,230
.
The FDA advisory panel voted ten to one,
704
00:30:31,297 --> 00:30:33,966
that flibanserin was not
significantly better
705
00:30:34,000 --> 00:30:35,067
than a placebo,
706
00:30:35,134 --> 00:30:37,003
and unanimously
that the benefits
707
00:30:37,036 --> 00:30:40,206
did not outweigh side effects
like dizziness, nausea,
708
00:30:40,239 --> 00:30:42,208
and fatigue.
709
00:30:42,274 --> 00:30:44,010
.
When the German company took it forward,
710
00:30:44,043 --> 00:30:47,146
they got a list of issues that
said go do one more study
711
00:30:47,179 --> 00:30:48,514
where you show desire
712
00:30:48,547 --> 00:30:51,550
and then also go do
a number of studies
713
00:30:51,583 --> 00:30:54,086
on healthy volunteers
looking at interactions
714
00:30:54,153 --> 00:30:55,254
with other drugs.
715
00:30:55,321 --> 00:30:58,090
And that's when Sprout took
it and did all that work.
716
00:30:58,157 --> 00:30:59,558
Then they brought
that back to FDA
717
00:30:59,625 --> 00:31:02,028
and now they get
rejected again,
718
00:31:02,061 --> 00:31:04,030
having done everything
FDA asked for.
719
00:31:04,063 --> 00:31:05,564
.
The FDA gave a red light
720
00:31:05,597 --> 00:31:08,734
to a drug meant to rev
up a woman's sex drive.
721
00:31:08,767 --> 00:31:12,038
The agency rejected a little
pink pill called Flibanserin
722
00:31:12,071 --> 00:31:14,140
saying it had
modest effectiveness.
723
00:31:14,173 --> 00:31:18,010
We've had biological solutions
and treatments for men.
724
00:31:18,044 --> 00:31:19,912
I think it's time for women.
725
00:31:19,979 --> 00:31:25,251
.
Erectile dysfunction was seen as an unmet physical ailment.
726
00:31:25,284 --> 00:31:31,523
Addyi was evaluated as an
unmet psychological ailment,
727
00:31:31,557 --> 00:31:35,561
which immediately triggers
a higher standard of review
728
00:31:35,594 --> 00:31:37,563
and additional safety measures.
729
00:31:38,430 --> 00:31:40,866
.
They said it had to be ultra safe
730
00:31:40,899 --> 00:31:44,003
because women were
taking it every day.
731
00:31:44,036 --> 00:31:49,308
And so, they generated a lot
of concerns about things like
732
00:31:49,375 --> 00:31:51,077
use with alcohol.
733
00:31:51,110 --> 00:31:54,947
Addyi is alleged to have this
shocking alcohol interaction
734
00:31:55,014 --> 00:31:56,615
that we can't accept,
735
00:31:56,648 --> 00:32:00,252
when the data are almost
exactly the data of Cialis.
736
00:32:00,286 --> 00:32:01,620
And when you look at Cialis,
737
00:32:01,687 --> 00:32:04,390
it essentially says men
should not binge drink.
738
00:32:04,423 --> 00:32:08,560
.
"You shouldn't consume if you've had more than five
739
00:32:08,594 --> 00:32:10,229
"alcoholic beverages."
740
00:32:10,262 --> 00:32:13,432
So women can't have any
and men can have five
741
00:32:13,465 --> 00:32:15,134
and still take it.
742
00:32:15,167 --> 00:32:16,935
Well it's probably not
gonna work very well
743
00:32:16,969 --> 00:32:20,772
in that circumstance for
an erection, but okay.
744
00:32:20,806 --> 00:32:24,110
.
Another example is that flibanserin makes you sleepy.
745
00:32:24,143 --> 00:32:26,112
That is a labelled side effect,
746
00:32:26,145 --> 00:32:29,148
we know that that's why you
take it right before bed.
747
00:32:29,215 --> 00:32:31,183
And we had shown
748
00:32:31,250 --> 00:32:32,318
that there were more sex,
749
00:32:32,351 --> 00:32:34,153
satisfying sexual events
when you were on flibanserin
750
00:32:34,220 --> 00:32:35,187
than when you weren't.
751
00:32:35,254 --> 00:32:36,822
And one of the FDA
reviewers said,
752
00:32:36,888 --> 00:32:40,092
"Well couldn't that be because
the women are just too sleepy
753
00:32:40,126 --> 00:32:42,194
"to fight off their husbands?"
754
00:32:42,261 --> 00:32:44,363
First of all, I don't believe
we have husband rapists
755
00:32:44,430 --> 00:32:45,331
at large in this country.
756
00:32:45,397 --> 00:32:46,798
But, but beyond that,
757
00:32:46,832 --> 00:32:48,234
you know, I just thought,
758
00:32:48,267 --> 00:32:50,269
if everybody could just think
about their personal situation
759
00:32:50,302 --> 00:32:51,470
for a moment,
760
00:32:51,503 --> 00:32:53,205
the wife is sleepy,
761
00:32:53,272 --> 00:32:55,041
are we having more
sex or less sex?
762
00:32:55,107 --> 00:32:57,176
The notion that
the wife is sleepy
763
00:32:57,243 --> 00:32:58,644
so we must be
having more sex,
764
00:32:58,677 --> 00:33:03,049
like you're refusing to
accept that this is real data.
765
00:33:03,115 --> 00:33:05,817
Like so when you see data
that answers the question,
766
00:33:05,851 --> 00:33:07,386
yes, they're having more sex,
767
00:33:07,453 --> 00:33:10,189
you immediately are looking
for a way to discount it.
768
00:33:10,222 --> 00:33:13,159
Their concern with
sedation was,
769
00:33:13,192 --> 00:33:15,194
and they literally said this,
770
00:33:15,261 --> 00:33:19,265
that a woman might take
flibanserin the night before
771
00:33:19,298 --> 00:33:20,399
and get up in the morning
772
00:33:20,466 --> 00:33:23,502
and fall asleep driving
her kids to school.
773
00:33:24,770 --> 00:33:26,172
It was very much like,
774
00:33:26,205 --> 00:33:28,640
well, we need to sort
of protect women
775
00:33:28,674 --> 00:33:30,709
because they might
not remember,
776
00:33:30,742 --> 00:33:34,180
they might not make good
choices about taking this,
777
00:33:34,213 --> 00:33:36,048
and it's so dangerous.
778
00:33:36,082 --> 00:33:39,017
So we did a driving
study and lo and behold,
779
00:33:39,051 --> 00:33:43,422
women drove better
taking Addyi than placebo.
780
00:33:43,489 --> 00:33:45,091
And that's not surprising
781
00:33:45,157 --> 00:33:48,860
'cause if you have a better
deeper night's sleep, um,
782
00:33:48,894 --> 00:33:51,363
your reaction time in
the morning is improved.
783
00:33:51,397 --> 00:33:54,766
You know, the driving study
was over a million dollars,
784
00:33:54,833 --> 00:33:56,502
which we have so many drugs,
785
00:33:56,535 --> 00:33:58,604
all the anti-depressants
cause sedation.
786
00:33:59,505 --> 00:34:00,739
And no one said,
787
00:34:00,772 --> 00:34:02,408
go make sure,
you know, you're,
788
00:34:02,474 --> 00:34:04,410
you're not gonna be
impaired the next morning.
789
00:34:04,476 --> 00:34:06,678
The reason here was,
well these are women
790
00:34:06,712 --> 00:34:08,547
who could be driving
their kids to school.
791
00:34:08,580 --> 00:34:13,119
And it's that paternalistic
lens over women's health, right?
792
00:34:13,185 --> 00:34:15,053
That it's, it's not
about the woman,
793
00:34:15,087 --> 00:34:17,356
it's about the people
she touches in her life
794
00:34:17,389 --> 00:34:19,057
and also protecting them.
795
00:34:19,091 --> 00:34:20,459
And that's inappropriate, right?
796
00:34:20,526 --> 00:34:22,894
A drug is, is approved
as safe and effective
797
00:34:22,928 --> 00:34:24,963
for the people who take it.
798
00:34:25,597 --> 00:34:27,333
.
It's the little pink pill.
799
00:34:27,366 --> 00:34:29,235
And this one is
for the ladies.
800
00:34:29,268 --> 00:34:33,205
It works on key chemicals in
the brain to increase desire.
801
00:34:33,239 --> 00:34:36,942
They, they had a desire
before and they've lost that
802
00:34:36,975 --> 00:34:39,945
and it's really causing
pretty profound distress,
803
00:34:39,978 --> 00:34:43,215
either for them personally or
in their relationship dynamic.
804
00:34:43,249 --> 00:34:46,118
.
Enter the pink pill known as flibanserin.
805
00:34:46,152 --> 00:34:47,953
Cindy Whitehead bought
the rights to it
806
00:34:47,986 --> 00:34:51,290
and has been working for three
years to get FDA approval.
807
00:34:51,357 --> 00:34:54,560
The last trial of a thousand
women showed promising results.
808
00:34:55,794 --> 00:34:59,465
.
FDA insisted that we measure satisfying sexual events.
809
00:34:59,498 --> 00:35:01,333
We had to show an improvement
810
00:35:01,400 --> 00:35:03,469
in how many satisfying
sexual events we were having,
811
00:35:03,535 --> 00:35:05,070
and we showed it, right?
812
00:35:05,103 --> 00:35:06,972
That was, I think it
was one more per month
813
00:35:07,038 --> 00:35:09,408
and FDA's like oh,
one more per month.
814
00:35:09,441 --> 00:35:11,310
And in essence, the
FDA had said to us,
815
00:35:11,343 --> 00:35:14,480
well, we feel the
effect is only modest
816
00:35:14,513 --> 00:35:17,316
and therefore no risk
would be worth it.
817
00:35:17,383 --> 00:35:19,418
So we said to the FDA,
hold on,
818
00:35:19,451 --> 00:35:22,288
what do you mean that
the effect is modest?
819
00:35:22,321 --> 00:35:23,322
It is true
820
00:35:23,389 --> 00:35:26,325
that Addyi doesn't take you
from being having no sex
821
00:35:26,392 --> 00:35:27,959
to being a nymphomaniac.
822
00:35:27,993 --> 00:35:29,127
Actually, that would be bad.
823
00:35:29,161 --> 00:35:31,197
We have to measure for that
in clinical trials, right?
824
00:35:31,263 --> 00:35:33,299
It takes you from
a place in which
825
00:35:33,332 --> 00:35:34,366
you're not thinking about sex
826
00:35:34,433 --> 00:35:36,435
to where you are
thinking about sex.
827
00:35:36,468 --> 00:35:39,338
Society thinks of sex
as a performative act,
828
00:35:39,371 --> 00:35:40,872
there's a destination.
829
00:35:40,939 --> 00:35:42,841
And really what
this was addressing
830
00:35:42,874 --> 00:35:47,112
was the brain being
in the right place
831
00:35:47,145 --> 00:35:48,414
to have spontaneous interest
832
00:35:48,447 --> 00:35:51,217
to respond to a
partner's advance,
833
00:35:51,283 --> 00:35:53,552
to want to initiate something.
834
00:35:53,619 --> 00:35:57,423
So like everything being
so performance driven
835
00:35:57,456 --> 00:35:59,157
was really a male metric.
836
00:35:59,191 --> 00:36:02,228
.
The studies show that there's an increase in, on average,
837
00:36:02,294 --> 00:36:04,863
one sexually satisfying
encounter a month.
838
00:36:04,896 --> 00:36:06,398
And a lot of folks
will hear that and say,
839
00:36:06,465 --> 00:36:08,300
one encounter a month,
that's very little,
840
00:36:08,334 --> 00:36:10,402
but how is that even worth it?
841
00:36:10,469 --> 00:36:13,305
And my response to
that typically is,
842
00:36:13,339 --> 00:36:15,374
when we're treating
somebody who has HSDD,
843
00:36:15,407 --> 00:36:17,042
they'll be lucky
if they have sex
844
00:36:17,075 --> 00:36:18,844
once or twice a
year typically.
845
00:36:18,877 --> 00:36:23,215
Once a month is a monstrous
change for some of these, uh,
846
00:36:23,249 --> 00:36:24,182
these couples.
847
00:36:26,184 --> 00:36:28,554
.
We've always prioritized our sex life
848
00:36:28,587 --> 00:36:31,056
and it's something
we don't wanna lose.
849
00:36:31,122 --> 00:36:32,558
- We met in college.
- Yeah.
850
00:36:32,591 --> 00:36:34,393
- Um...
- Grad school.
851
00:36:34,460 --> 00:36:35,861
Grad school.
852
00:36:35,894 --> 00:36:38,897
Both studying
the same subject,
853
00:36:38,964 --> 00:36:42,668
and we didn't hit
it off right away,
854
00:36:42,701 --> 00:36:46,672
but, um, once we, uh, got
together we've been inseparable
855
00:36:47,573 --> 00:36:52,411
and, um, well our
relationship was fine, um,
856
00:36:52,478 --> 00:36:58,617
but our sex life had,
had dwindled, um,
857
00:36:58,684 --> 00:37:00,252
and it was frustrating
of course,
858
00:37:00,319 --> 00:37:02,621
but then, um, you know,
859
00:37:02,688 --> 00:37:04,390
I was going through
a change too.
860
00:37:04,423 --> 00:37:07,225
And so, every month I was
going and getting tested,
861
00:37:07,259 --> 00:37:09,461
um, for testosterone levels.
862
00:37:09,528 --> 00:37:12,298
And I think we were both
experiencing our own versions
863
00:37:12,364 --> 00:37:13,899
of menopause, um,
864
00:37:13,932 --> 00:37:17,736
and our libidos seemed
to be out of sync.
865
00:37:17,769 --> 00:37:23,275
Um, David got involved in some
treatment that increased his,
866
00:37:23,342 --> 00:37:26,378
and mine was still
laxing there behind.
867
00:37:26,412 --> 00:37:31,049
And, um, I had one,
um, gynecologist, um,
868
00:37:31,082 --> 00:37:37,489
but she didn't try to
educate me beyond, um,
869
00:37:37,556 --> 00:37:40,492
I think she said
something to the effect of,
870
00:37:40,559 --> 00:37:42,561
um, you're at a approaching
a period of time
871
00:37:42,594 --> 00:37:45,431
where hormones probably wouldn't
make more sense for you.
872
00:37:47,198 --> 00:37:48,434
.
So clearly you can see,
873
00:37:48,467 --> 00:37:50,168
despite the wonderful
job with my makeup,
874
00:37:50,235 --> 00:37:52,304
that I'm a menopausal woman.
875
00:37:52,338 --> 00:37:53,339
And for those who think
876
00:37:53,405 --> 00:37:54,506
that after your hot
flashes are gone
877
00:37:54,573 --> 00:37:55,941
menopause is over,
878
00:37:55,974 --> 00:37:57,476
no, you're in menopause
for the rest of your life
879
00:37:57,543 --> 00:37:59,511
until you die.
880
00:37:59,578 --> 00:38:00,946
But just because
you're menopausal
881
00:38:00,979 --> 00:38:03,482
doesn't mean you don't
have a right to great sex.
882
00:38:04,383 --> 00:38:05,317
My whole life and
my whole training
883
00:38:05,384 --> 00:38:07,819
menopause was treated
as a footnote.
884
00:38:07,853 --> 00:38:09,120
In my field it was like,
885
00:38:09,154 --> 00:38:12,257
use lube as though that would
solve all the solutions
886
00:38:12,290 --> 00:38:13,559
to do with your shoulder,
887
00:38:13,592 --> 00:38:14,660
to do with your brain fog,
888
00:38:14,693 --> 00:38:16,995
to do with the way
alcohol affects you,
889
00:38:17,028 --> 00:38:18,964
the fact that you
can't sleep at night.
890
00:38:18,997 --> 00:38:21,132
And now we're in this moment
891
00:38:21,166 --> 00:38:23,569
where we're talking about
perimenopause and menopause
892
00:38:23,602 --> 00:38:25,604
and it's pissing
some people off.
893
00:38:25,637 --> 00:38:27,606
They're wondering why are
you being so loud about it?
894
00:38:27,639 --> 00:38:28,807
Well, the real question is,
895
00:38:28,840 --> 00:38:31,677
why were we forced to be so
quiet about it for so long?
896
00:38:32,378 --> 00:38:36,047
Postmenopausal patients
are considered irrelevant
897
00:38:36,114 --> 00:38:39,317
when it comes to sexual
health in our society.
898
00:38:39,351 --> 00:38:41,987
It is not only by our society,
899
00:38:42,020 --> 00:38:43,254
but patients within themselves
900
00:38:43,288 --> 00:38:45,290
don't feel like
they deserve sex.
901
00:38:45,323 --> 00:38:46,358
They don't deserve intimacy.
902
00:38:46,425 --> 00:38:48,494
They don't deserve
pleasure, connection.
903
00:38:48,527 --> 00:38:51,863
I had a patient come in
just the other day who said,
904
00:38:51,897 --> 00:38:54,966
"I shouldn't even be having
sex anymore, right?"
905
00:38:55,000 --> 00:38:58,537
And I mean, my, my
mouth is open for them
906
00:38:58,604 --> 00:38:59,638
because I'm just like,
907
00:38:59,671 --> 00:39:03,542
I don't understand how
this can be so ingrained
908
00:39:03,575 --> 00:39:04,676
in everything that we do
909
00:39:04,710 --> 00:39:07,212
that even patients feel
that they don't deserve it.
910
00:39:07,278 --> 00:39:10,682
And I think that's what's
so heartbreaking, um,
911
00:39:10,716 --> 00:39:14,553
is to see that people don't
even value themselves
912
00:39:14,586 --> 00:39:17,856
because our society has
so clearly told them
913
00:39:17,889 --> 00:39:20,926
that they are no longer a
valued part of the society.
914
00:39:23,228 --> 00:39:24,863
.
When you look at women:
915
00:39:24,896 --> 00:39:27,633
premenopausal,
postmenopausal,
916
00:39:27,666 --> 00:39:29,535
transgender individuals,
917
00:39:29,568 --> 00:39:33,238
the conversation of what
is available for you
918
00:39:33,271 --> 00:39:36,207
is not dictated by you.
919
00:39:36,241 --> 00:39:39,244
If you are a
cisgendered white male,
920
00:39:39,310 --> 00:39:40,546
the healthcare in
the United States
921
00:39:40,579 --> 00:39:42,714
is pretty darn good
922
00:39:42,748 --> 00:39:48,053
and your healthcare experience
can be a uniquely personal one.
923
00:39:48,086 --> 00:39:49,721
.
Twenty-six to zero,
924
00:39:49,755 --> 00:39:51,923
that represents how
many drugs are available
925
00:39:51,957 --> 00:39:53,925
to treat male
sexual dysfunction,
926
00:39:53,959 --> 00:39:55,961
compared to those
that treat women's.
927
00:39:57,128 --> 00:40:00,932
.
When I started, there were 25 FDA approved drugs for men.
928
00:40:00,966 --> 00:40:03,735
When we were going through this,
and in our appeal,
929
00:40:03,769 --> 00:40:06,805
the 26th drug for
men came to market
930
00:40:06,872 --> 00:40:09,074
and it's for curvature
of the penis
931
00:40:09,107 --> 00:40:11,877
that interferes with
your enjoyment of sex.
932
00:40:11,910 --> 00:40:15,113
Okay, so that typically had
to be corrected surgically
933
00:40:15,146 --> 00:40:17,048
and now there was a
different and simpler option.
934
00:40:17,082 --> 00:40:18,116
Great.
935
00:40:18,183 --> 00:40:22,420
So the studies were on
around a thousand or so men
936
00:40:22,454 --> 00:40:26,658
and it had a pretty important
but rare side effect,
937
00:40:26,725 --> 00:40:29,160
and that was penile rupture.
938
00:40:29,227 --> 00:40:31,497
So let me get this straight,
939
00:40:31,563 --> 00:40:34,132
we can give men a product
and their dick can explode,
940
00:40:34,165 --> 00:40:36,502
but women can't have the
seven dwarfs of side effects
941
00:40:36,568 --> 00:40:38,570
like sleepy, dizzy, nausea.
942
00:40:38,604 --> 00:40:42,307
Twenty-six times we
had done that for men.
943
00:40:42,373 --> 00:40:46,612
So guys, it's just
you and your honey.
944
00:40:46,645 --> 00:40:48,747
Setting is perfect.
945
00:40:48,780 --> 00:40:52,484
But then erectile
dysfunction happens again.
946
00:40:52,551 --> 00:40:55,320
.
Viagra at that point had done so many commercials
947
00:40:55,353 --> 00:40:58,590
and, you know, we laughed
about the Viagra ads at the time
948
00:40:58,624 --> 00:41:01,326
that were basically
conditioning women
949
00:41:01,359 --> 00:41:03,695
to let men know all
their choices, um,
950
00:41:03,762 --> 00:41:05,831
while not asking the
question, where's mine?
951
00:41:05,897 --> 00:41:06,832
You know what?
952
00:41:06,898 --> 00:41:08,266
Plenty of guys
have this issue,
953
00:41:08,299 --> 00:41:09,668
not just getting an erection,
954
00:41:09,735 --> 00:41:10,936
but keeping it.
955
00:41:10,969 --> 00:41:14,840
Well Viagra helps guys with
ED get and keep an erection.
956
00:41:16,808 --> 00:41:21,847
I'm a beautiful woman
laying in a bed talking about
957
00:41:21,913 --> 00:41:23,582
your erection.
958
00:41:24,516 --> 00:41:25,884
Erection.
959
00:41:29,354 --> 00:41:30,689
Now that they're distracted,
960
00:41:30,722 --> 00:41:33,024
let's do something
to change this.
961
00:41:33,058 --> 00:41:34,693
Women deserve better.
962
00:41:34,726 --> 00:41:36,261
Let's even the score.
963
00:41:37,563 --> 00:41:38,830
Stop!
964
00:41:38,864 --> 00:41:42,000
Sprout initiated something
called "even the score."
965
00:41:42,033 --> 00:41:44,670
This was a advocacy campaign
966
00:41:44,703 --> 00:41:47,338
to try to get people
to understand
967
00:41:47,372 --> 00:41:52,377
that this is a critical issue
for 10% or more of women.
968
00:41:52,443 --> 00:41:54,379
Are we really so behind
969
00:41:54,412 --> 00:41:57,549
that we don't think women have
the right to sexual desire?
970
00:41:57,583 --> 00:42:00,619
Yet again we come second.
971
00:42:01,920 --> 00:42:03,922
.
Men who take erectile dysfunction medication
972
00:42:03,989 --> 00:42:05,490
may find it entirely useless
973
00:42:05,523 --> 00:42:08,193
if their partner does not
have any sexual desire.
974
00:42:08,226 --> 00:42:10,729
Options for women have been
through rigorous trials
975
00:42:10,762 --> 00:42:12,931
and show less
serious side effects.
976
00:42:12,998 --> 00:42:14,700
Safe and effective
sexual health medication
977
00:42:14,733 --> 00:42:16,768
could help thousands of
women and their partners
978
00:42:16,835 --> 00:42:18,837
enjoy a healthy sex life.
979
00:42:20,238 --> 00:42:21,707
Men have a little blue pill,
980
00:42:21,740 --> 00:42:24,375
so why not a little
pink pill for the ladies?
981
00:42:24,409 --> 00:42:28,213
.
Sprout really helped in bringing the conversation
982
00:42:28,246 --> 00:42:30,181
into the media
983
00:42:30,215 --> 00:42:34,886
and into the living rooms
and awareness of people.
984
00:42:34,920 --> 00:42:36,588
- Flibanserin.
- Flibanserin.
985
00:42:36,622 --> 00:42:37,889
Flibanserin.
986
00:42:37,923 --> 00:42:39,725
.
Now it is expected to be marketed under the name,
987
00:42:39,758 --> 00:42:41,092
Addyi-1.
988
00:42:41,126 --> 00:42:43,629
.
It became a very public conversation.
989
00:42:43,695 --> 00:42:45,563
Here's this little
private company
990
00:42:45,597 --> 00:42:46,932
in Raleigh, North Carolina,
991
00:42:46,998 --> 00:42:49,701
and all of a sudden Nightline
shows up at my door.
992
00:42:49,735 --> 00:42:52,337
They're like, who are you
and what's happening here?
993
00:42:52,370 --> 00:42:54,740
.
It's known as Viagra for women,
994
00:42:54,773 --> 00:42:58,744
a tiny tablet that could have
a huge impact in the bedroom.
995
00:42:58,777 --> 00:43:01,046
I think this is
absolutely an evolution
996
00:43:01,079 --> 00:43:03,114
in the female
sexual revolution.
997
00:43:03,148 --> 00:43:06,618
.
But you won't be able to get the pink pill just yet
998
00:43:06,685 --> 00:43:08,754
because the drug is
locked in a heated battle
999
00:43:08,787 --> 00:43:10,756
for FDA approval.
1000
00:43:10,789 --> 00:43:11,857
.
Once that happened, you know,
1001
00:43:11,890 --> 00:43:13,792
the public was
all weighing in.
1002
00:43:13,859 --> 00:43:15,260
.
There's a pill that's in development
1003
00:43:15,293 --> 00:43:16,427
not FDA approved yet.
1004
00:43:16,461 --> 00:43:18,063
Woo! For women? Like Viagra?
1005
00:43:18,096 --> 00:43:19,597
There you go.
1006
00:43:19,631 --> 00:43:22,267
People are like, aw,
the little pink pill.
1007
00:43:22,300 --> 00:43:23,301
So it's the little pink pill.
1008
00:43:23,368 --> 00:43:24,803
That little pink pill.
1009
00:43:24,870 --> 00:43:26,137
It's a little pink pill.
1010
00:43:26,171 --> 00:43:27,773
Oh the little pink pill.
1011
00:43:27,806 --> 00:43:29,775
It is the sing song
in their voice
1012
00:43:29,808 --> 00:43:30,776
and the pat on the shoulders.
1013
00:43:30,809 --> 00:43:32,310
It assumed weakness.
1014
00:43:32,343 --> 00:43:34,345
It assumed that
it was trivial.
1015
00:43:34,412 --> 00:43:35,647
Is there something to fix?
1016
00:43:35,714 --> 00:43:37,448
No, not at all.
1017
00:43:37,482 --> 00:43:39,851
.
And it was so dismissive.
1018
00:43:39,918 --> 00:43:42,020
.
Some doctors say flibanserin was rejected
1019
00:43:42,087 --> 00:43:43,755
for a very simple reason,
1020
00:43:43,789 --> 00:43:47,125
it's an ineffective drug
for a non-existent problem.
1021
00:43:47,158 --> 00:43:49,127
It's a classic
marketing technique
1022
00:43:49,160 --> 00:43:52,630
to first create a problem
and then sell the solution.
1023
00:43:52,664 --> 00:43:54,365
And that's what's
going on here.
1024
00:43:54,432 --> 00:43:56,134
What is this advocacy group?
1025
00:43:56,167 --> 00:43:58,503
Is it a Sprout PR campaign?
1026
00:43:58,536 --> 00:44:00,071
.
It looks like a Viagra ad,
1027
00:44:00,105 --> 00:44:02,841
but this parody is mocking
all those male pills
1028
00:44:02,908 --> 00:44:04,676
and their big
budget commercials.
1029
00:44:04,743 --> 00:44:06,511
Even the Score made the video,
1030
00:44:06,544 --> 00:44:09,480
a group backed by nonprofits
and pharmaceutical companies,
1031
00:44:09,514 --> 00:44:11,750
including the one
that makes Flibanserin,
1032
00:44:11,783 --> 00:44:13,819
the so-called
"Little Pink Pill."
1033
00:44:21,192 --> 00:44:23,361
.
You can make two choices in that moment, right?
1034
00:44:23,428 --> 00:44:27,165
You either let it set you
back and you lean back from it
1035
00:44:27,198 --> 00:44:28,700
or you lean right into it
1036
00:44:28,734 --> 00:44:30,769
and say, this is the
conversation we're gonna have.
1037
00:44:32,704 --> 00:44:35,606
I took my pink stilettos
and I started going to DC.
1038
00:44:36,975 --> 00:44:39,644
And I was knocking on the
doors of these giants
1039
00:44:39,677 --> 00:44:41,546
in women's rights
and women's health
1040
00:44:41,612 --> 00:44:44,215
and I was like, hi, I'm Cindy,
1041
00:44:44,249 --> 00:44:48,019
I have this company and here's
what this condition is.
1042
00:44:48,053 --> 00:44:50,121
And I went with Dr. Goldstein
1043
00:44:50,155 --> 00:44:54,225
so that they could ask an expert
any questions they might have.
1044
00:44:54,259 --> 00:44:57,362
And at the end of this meeting
a woman named Susan Scanlon
1045
00:44:57,395 --> 00:44:59,898
who ran the National Council
of Women's Organizations,
1046
00:44:59,931 --> 00:45:03,401
came over and she's like,
we're gonna fight this.
1047
00:45:07,739 --> 00:45:10,909
When we called it on
a double standard,
1048
00:45:10,976 --> 00:45:13,879
this group started
to come together.
1049
00:45:13,912 --> 00:45:17,615
Here were giants of
Women's Health and Rights,
1050
00:45:17,682 --> 00:45:19,217
Black Women's
Health Imperative,
1051
00:45:19,250 --> 00:45:20,919
Nurse Practitioners
in Women's Health,
1052
00:45:20,952 --> 00:45:22,620
Nurse-Midwives,
1053
00:45:22,687 --> 00:45:23,855
National Organization
for Women,
1054
00:45:23,889 --> 00:45:25,223
National Council of
Women's Organizations,
1055
00:45:25,256 --> 00:45:26,391
National Consumers League,
1056
00:45:26,424 --> 00:45:30,695
incredible like women
that were my heroes.
1057
00:45:33,264 --> 00:45:35,266
The FDA themselves
had deemed this
1058
00:45:35,300 --> 00:45:39,537
one of their top ten
areas of unmet need.
1059
00:45:39,570 --> 00:45:41,907
This issue is so prevalent
it affects so many women
1060
00:45:41,940 --> 00:45:44,575
that it was on
their top ten list,
1061
00:45:44,609 --> 00:45:46,845
and yet here we were
in this conversation.
1062
00:45:46,878 --> 00:45:49,614
So for all these
women's rights groups,
1063
00:45:49,647 --> 00:45:51,416
with Dr. Goldstein,
1064
00:45:51,449 --> 00:45:55,320
chartered a bus and demanded
a meeting with the FDA,
1065
00:45:59,124 --> 00:46:00,826
.
An FDA advisory panel today
1066
00:46:00,892 --> 00:46:03,261
hearing the pros and
cons of Flibanserin,
1067
00:46:03,294 --> 00:46:05,363
also known as the
female Viagra.
1068
00:46:06,965 --> 00:46:10,135
.
When we fought, other women fought.
1069
00:46:10,201 --> 00:46:12,637
.
Good morning, thank you for letting me speak.
1070
00:46:12,670 --> 00:46:14,772
I'm Susan Scanlon,
I'm Chair Emerita
1071
00:46:14,806 --> 00:46:17,943
of the National Council of
Women's Organizations.
1072
00:46:17,976 --> 00:46:20,178
I'm also chair of
Even The Score.
1073
00:46:21,980 --> 00:46:23,982
.
You know, I give all credit to Susan Scanlon,
1074
00:46:24,015 --> 00:46:26,952
who I'm so sad is
no longer with us.
1075
00:46:26,985 --> 00:46:30,621
She was larger than life,
with a voice to match,
1076
00:46:30,655 --> 00:46:35,827
and, you know, also a huge
mentor of mine in that she said,
1077
00:46:35,861 --> 00:46:38,663
"We're gonna call a
spade a spade here."
1078
00:46:38,696 --> 00:46:42,133
.
We're tired of hearing that female sexual health is complex
1079
00:46:42,167 --> 00:46:45,503
as if there would be no
answer if we didn't study it.
1080
00:46:45,536 --> 00:46:46,671
Make no mistake,
1081
00:46:46,704 --> 00:46:48,306
men are equally complex
1082
00:46:48,339 --> 00:46:50,775
and there's been no
shortage of medications
1083
00:46:50,808 --> 00:46:53,111
to address their
sexual dysfunction.
1084
00:46:53,144 --> 00:46:54,312
In 1960,
1085
00:46:54,345 --> 00:46:57,448
the birth control pill
precipitated a societal shift
1086
00:46:57,482 --> 00:47:01,019
to recognize women's rights
as reproductive beings.
1087
00:47:01,086 --> 00:47:04,990
In 2014, let's shift to
recognize women's rights
1088
00:47:05,023 --> 00:47:06,691
as sexual beings.
1089
00:47:06,724 --> 00:47:08,059
Thank you very much.
1090
00:47:10,695 --> 00:47:12,230
.
I would challenge anybody,
1091
00:47:12,297 --> 00:47:15,533
what is better than
to have advocacy?
1092
00:47:15,566 --> 00:47:16,534
The best things have happened
1093
00:47:16,601 --> 00:47:18,569
when patients have
taken the mic
1094
00:47:18,636 --> 00:47:20,638
and demanded
what they deserve.
1095
00:47:20,671 --> 00:47:22,740
My name is Judith,
I'm 66 years old
1096
00:47:22,807 --> 00:47:24,709
and I've been
dealing with FSD
1097
00:47:24,775 --> 00:47:27,012
on and off for 17 years.
1098
00:47:27,045 --> 00:47:30,481
Hi, I'm Katherine,
I'm from Indianapolis, Indiana.
1099
00:47:30,515 --> 00:47:34,019
I learned in high school sex
ed that a woman's sexual prime,
1100
00:47:34,052 --> 00:47:36,021
so to speak,
is in her thirties,
1101
00:47:36,054 --> 00:47:37,555
yet here I am.
1102
00:47:37,588 --> 00:47:40,725
.
It is amazing how many women of all ages I talked to
1103
00:47:40,758 --> 00:47:43,194
that have some
degree of HSDD,
1104
00:47:43,228 --> 00:47:47,832
this disorder is real
and we need a solution.
1105
00:47:47,865 --> 00:47:51,869
At that time, there was
a lot of feeling that
1106
00:47:51,903 --> 00:47:55,106
we were medicalizing HSDD.
1107
00:47:55,173 --> 00:47:56,975
And finally we have Susan.
1108
00:47:58,009 --> 00:47:59,077
Hi, I'm Susan.
1109
00:47:59,110 --> 00:48:02,280
I stopped having desire
for sex about two years
1110
00:48:02,347 --> 00:48:05,550
into my now 11-year
partnership with my husband.
1111
00:48:05,583 --> 00:48:07,385
My partner and I had
done work on ourselves
1112
00:48:07,418 --> 00:48:08,886
in a therapeutic setting.
1113
00:48:08,920 --> 00:48:11,556
We learned that our sexual
problems were a co-created
1114
00:48:11,589 --> 00:48:13,724
problem in our relationship.
1115
00:48:13,758 --> 00:48:15,560
.
Their idea was really that
1116
00:48:15,593 --> 00:48:17,895
it was saying
you have a condition
1117
00:48:17,929 --> 00:48:21,066
that they didn't have
because they were normal.
1118
00:48:21,099 --> 00:48:22,833
.
Clinical psychologist Leonore Tiefer
1119
00:48:22,867 --> 00:48:24,235
says Sprout has concocted
a women's rights issue
1120
00:48:24,269 --> 00:48:28,406
to guilt the FDA into
approving flibanserin.
1121
00:48:28,439 --> 00:48:32,877
It's just a mishmash
of politics and science
1122
00:48:32,910 --> 00:48:35,113
and sex and money.
1123
00:48:35,180 --> 00:48:36,414
Money, money, money.
1124
00:48:36,447 --> 00:48:38,916
.
The FDA's ruling is due later this month.
1125
00:48:38,950 --> 00:48:42,954
.
Some people felt like women's desire was more complicated
1126
00:48:43,021 --> 00:48:45,756
and we shouldn't be
medicating women
1127
00:48:45,790 --> 00:48:48,159
because oftentimes their
desire can get better
1128
00:48:48,226 --> 00:48:50,228
if they're working
with a therapist
1129
00:48:50,261 --> 00:48:52,597
or you know, seeing a couple's
therapist with their partner.
1130
00:48:52,630 --> 00:48:54,632
.
This busy mom of four, Amanda Parrish,
1131
00:48:54,665 --> 00:48:57,602
says she used to have
a smouldering sex life
1132
00:48:57,635 --> 00:48:59,037
with her husband.
1133
00:48:59,070 --> 00:49:01,806
.
This drug isn't necessarily going to treat the fatigue
1134
00:49:01,872 --> 00:49:03,641
that might be giving
you a low sex drive
1135
00:49:03,674 --> 00:49:06,311
or you know, the kids that
you have running around
1136
00:49:06,377 --> 00:49:08,579
or the partner who
isn't helping you out
1137
00:49:08,613 --> 00:49:09,814
with the chores
around the house.
1138
00:49:09,847 --> 00:49:11,082
.
That's totally true.
1139
00:49:11,116 --> 00:49:16,154
But why shouldn't we
offer a medication
1140
00:49:16,221 --> 00:49:18,823
that has been shown,
clinically proven,
1141
00:49:18,856 --> 00:49:20,158
to help increase desire?
1142
00:49:20,191 --> 00:49:22,327
Not to say that it's
one or the other.
1143
00:49:22,360 --> 00:49:24,462
In fact, I think most people
that prescribe this medication
1144
00:49:24,495 --> 00:49:25,663
would say,
1145
00:49:25,696 --> 00:49:27,632
keeping that
therapy stuff around
1146
00:49:27,665 --> 00:49:29,634
is really important, right?
1147
00:49:29,667 --> 00:49:33,238
But if you can provide
a medical solution
1148
00:49:33,271 --> 00:49:37,008
in conjunction with
psychological treatments,
1149
00:49:37,075 --> 00:49:39,344
why would we deny women that?
1150
00:49:39,377 --> 00:49:41,646
Women don't need treatments
with real side effects
1151
00:49:41,679 --> 00:49:44,349
for imaginary diseases
invented by marketers.
1152
00:49:44,415 --> 00:49:47,185
.
If you've never experienced HSDD,
1153
00:49:47,218 --> 00:49:48,686
you don't understand
what it is.
1154
00:49:48,719 --> 00:49:49,987
.
It is a thinly veiled,
1155
00:49:50,021 --> 00:49:53,191
profit-driven marketing
campaign filled with bias,
1156
00:49:53,258 --> 00:49:56,161
misleading,
unsubstantiated information.
1157
00:49:56,194 --> 00:49:58,096
I think it's a scam.
1158
00:49:58,129 --> 00:50:02,300
To have a community fighting
and saying we were medicalizing
1159
00:50:02,333 --> 00:50:04,202
and claiming this wasn't
a biologic problem.
1160
00:50:04,235 --> 00:50:07,138
Well I will tell you it's
a, it's in your brain.
1161
00:50:07,172 --> 00:50:10,308
The language I like to use when
they say it's all in your head,
1162
00:50:10,341 --> 00:50:12,710
well, your brain is
up in your head.
1163
00:50:12,777 --> 00:50:13,744
This is your brain.
1164
00:50:13,811 --> 00:50:14,745
We live in a world
1165
00:50:14,812 --> 00:50:16,747
where women should have
a choice for their body
1166
00:50:16,814 --> 00:50:18,149
and they should
be able to choose
1167
00:50:18,183 --> 00:50:20,318
if they wanna take a a pill,
1168
00:50:20,351 --> 00:50:23,054
an injection, sex therapy,
1169
00:50:23,121 --> 00:50:24,255
or all of them.
1170
00:50:24,322 --> 00:50:25,923
But who is anyone
else to tell me?
1171
00:50:25,990 --> 00:50:27,225
And that's what angered me.
1172
00:50:27,258 --> 00:50:31,028
Who is that anyone else to tell
me I have a biologic problem?
1173
00:50:31,062 --> 00:50:32,563
I know that I was
functional before.
1174
00:50:32,597 --> 00:50:34,265
I know it's not in
my relationship.
1175
00:50:34,332 --> 00:50:36,067
I know something's changed.
1176
00:50:36,101 --> 00:50:38,736
Who is gonna tell me I
can't do something about it?
1177
00:50:38,769 --> 00:50:44,008
So the mood of the FDA
was very much a combative
1178
00:50:44,041 --> 00:50:47,678
that either you believed
in a biologic treatment
1179
00:50:47,712 --> 00:50:48,713
or you believed
1180
00:50:48,746 --> 00:50:51,382
that you shouldn't have
a biologic treatment.
1181
00:50:51,416 --> 00:50:53,551
.
A major medical headline tonight involving women,
1182
00:50:53,584 --> 00:50:55,920
the drug nicknamed
the Little Pink Pill.
1183
00:50:55,986 --> 00:50:58,022
A key decision today.
1184
00:50:58,055 --> 00:51:00,091
.
FDA advisors will once again consider
1185
00:51:00,158 --> 00:51:04,395
whether to approve a drug that's
already been rejected twice.
1186
00:51:04,429 --> 00:51:06,063
.
Women now once step closer
1187
00:51:06,097 --> 00:51:08,299
with joining their
frisky male counterparts
1188
00:51:08,366 --> 00:51:10,935
who've enjoyed the benefits of
pills to help their sex lives
1189
00:51:10,968 --> 00:51:12,370
for years.
1190
00:51:13,003 --> 00:51:15,306
.
I arrived at FDA when the doors opened
1191
00:51:15,373 --> 00:51:17,275
and then as people started
to come, they were like,
1192
00:51:17,342 --> 00:51:20,411
you know, there's people on the
road, um, leading into the FDA
1193
00:51:20,445 --> 00:51:22,079
with signs and banners
1194
00:51:22,113 --> 00:51:24,449
and like, I think it's
gonna be a tough day.
1195
00:51:27,418 --> 00:51:29,954
I was in my urology
training at Georgetown
1196
00:51:29,987 --> 00:51:32,757
and so I was in the
Washington DC area
1197
00:51:32,790 --> 00:51:35,092
and it just felt important.
1198
00:51:35,126 --> 00:51:37,595
I can't describe it,
but it felt historical.
1199
00:51:38,363 --> 00:51:39,764
.
Good morning.
1200
00:51:39,797 --> 00:51:42,400
We have a very full agenda.
1201
00:51:42,433 --> 00:51:45,002
Welcome to the
Drugs Advisory Committee.
1202
00:51:45,803 --> 00:51:47,205
.
It was straight out of a movie.
1203
00:51:47,238 --> 00:51:49,274
FDA's never seen
crowds like this.
1204
00:51:49,307 --> 00:51:52,510
The press were showing up,
everybody was in this room
1205
00:51:52,577 --> 00:51:55,646
and it feels a little bit like
you're at the Supreme Court.
1206
00:51:57,081 --> 00:51:59,317
.
The first FDA meeting I went to with Cindy,
1207
00:51:59,350 --> 00:52:01,952
you know, I had at that point
met her a number of times
1208
00:52:01,986 --> 00:52:03,120
in person.
1209
00:52:03,154 --> 00:52:05,356
She was oddly always
wearing pink.
1210
00:52:05,423 --> 00:52:06,257
And so I had this concern
1211
00:52:06,291 --> 00:52:08,259
that she was gonna
wear pink to FDA,
1212
00:52:08,293 --> 00:52:11,296
and so I got up my nerve
to tell her, so don't,
1213
00:52:11,329 --> 00:52:14,865
don't wear pink to FDA
because you won't be credible.
1214
00:52:14,932 --> 00:52:18,002
And she really didn't
say yes or no,
1215
00:52:18,035 --> 00:52:19,870
but she showed up
the next day in pink.
1216
00:52:21,172 --> 00:52:22,773
.
When I showed up at FDA meetings
1217
00:52:22,807 --> 00:52:25,176
and my pink got brighter
and brighter and brighter
1218
00:52:25,243 --> 00:52:27,011
until you could see
it from outer space.
1219
00:52:27,044 --> 00:52:29,780
To me it was about
being unapologetic
1220
00:52:29,814 --> 00:52:31,782
and actually what
was at the root of that
1221
00:52:31,816 --> 00:52:34,285
was the conversation
we needed to have.
1222
00:52:34,319 --> 00:52:36,221
.
I will tell you that the morning of the advisory committee,
1223
00:52:36,287 --> 00:52:37,455
I mean, it was very tense
1224
00:52:37,488 --> 00:52:39,857
and I was in my black
suit and my beige shirt,
1225
00:52:39,890 --> 00:52:43,361
and I just went up to her and
I knelt down right next to her
1226
00:52:43,394 --> 00:52:44,395
and I just said,
1227
00:52:44,462 --> 00:52:46,464
"I'm wearing pink underwear."
1228
00:52:46,497 --> 00:52:48,533
Like just to like,
lighten the mood,
1229
00:52:48,599 --> 00:52:50,835
which was like also
happened to be true.
1230
00:52:50,868 --> 00:52:53,371
Thank you Dr. Lewis
and good morning.
1231
00:52:53,404 --> 00:52:55,440
I'd like to take a moment.
I'm Josephine Torrente,
1232
00:52:55,473 --> 00:52:56,507
Executive Vice President
1233
00:52:56,541 --> 00:52:58,676
of Corporate and
Regulatory Affairs
1234
00:52:58,709 --> 00:53:00,578
at Sprout Pharmaceuticals.
1235
00:53:00,645 --> 00:53:04,815
The first statement
by FDA was a defence
1236
00:53:04,849 --> 00:53:06,451
that they are not
in fact biassed.
1237
00:53:07,385 --> 00:53:11,622
So, uh, some have claimed
gender bias on the part of FDA
1238
00:53:11,656 --> 00:53:15,893
when it comes to treatments
for female sexual dysfunction.
1239
00:53:15,926 --> 00:53:19,430
The FDA firmly rejects
this assertion.
1240
00:53:19,497 --> 00:53:22,066
FDA is always concerned
with unmet needs,
1241
00:53:22,132 --> 00:53:25,836
whether this is in women,
men or in children.
1242
00:53:25,870 --> 00:53:29,874
.
The fact that FDA felt the pressure to say,
1243
00:53:29,907 --> 00:53:32,610
"We are not biassed
against women's health,"
1244
00:53:32,677 --> 00:53:36,414
just tells you the impact
that these women were having
1245
00:53:36,447 --> 00:53:39,384
by going to FDA and saying,
we need a drug for this.
1246
00:53:39,417 --> 00:53:41,252
Don't diminish the benefit.
1247
00:53:50,261 --> 00:53:51,429
Good afternoon.
My name is Barbara.
1248
00:53:51,496 --> 00:53:52,463
I'm a nurse.
1249
00:53:52,530 --> 00:53:53,564
This is my daughter Vicky,
1250
00:53:53,598 --> 00:53:56,467
and we are patients
of Dr. Goldstein
1251
00:53:56,534 --> 00:54:00,438
and we have no interest in
the outcome of this meeting.
1252
00:54:00,505 --> 00:54:02,072
I'm Amanda Parrish.
1253
00:54:02,106 --> 00:54:04,942
I am one of the
lucky 11,000 women
1254
00:54:04,975 --> 00:54:07,745
that was a patient on the
Flibanserin clinical trial.
1255
00:54:07,778 --> 00:54:09,980
I'm here with my husband Ben.
1256
00:54:10,047 --> 00:54:13,250
We funded our own trip and
we have no financial stake
1257
00:54:13,284 --> 00:54:14,885
at the outcome of this meeting.
1258
00:54:14,919 --> 00:54:17,121
Hi, my name is
Katherine Campbell.
1259
00:54:17,154 --> 00:54:20,257
My travel expenses are
being reimbursed by Sprout.
1260
00:54:20,291 --> 00:54:22,427
I hope everyone understands
that my husband and I
1261
00:54:22,460 --> 00:54:25,730
do not have money set aside
to fly back and forth to DC
1262
00:54:25,763 --> 00:54:28,799
so that I can talk about how
much sex we're not having.
1263
00:54:29,467 --> 00:54:34,104
.
Here you are with women who've taken time off work,
1264
00:54:34,138 --> 00:54:35,773
had somebody
babysit the kids,
1265
00:54:35,806 --> 00:54:38,309
potentially fly
across country
1266
00:54:38,343 --> 00:54:41,312
to reveal their most
private struggle
1267
00:54:41,346 --> 00:54:45,483
behind the closed doors of their
bedroom at a federal agency.
1268
00:54:45,550 --> 00:54:46,451
My name is Kelly Stapp
1269
00:54:46,484 --> 00:54:48,653
and I have no financial
things to disclose,
1270
00:54:48,686 --> 00:54:51,456
but I will disclose the fact
that I'm a bit scared to death
1271
00:54:51,489 --> 00:54:53,958
to stand up here and
talk about this.
1272
00:54:53,991 --> 00:54:57,795
.
Can you imagine like how just awkward, uncomfortable,
1273
00:54:57,828 --> 00:55:00,698
brave it was for
them to do that?
1274
00:55:00,765 --> 00:55:02,467
They're the heroes
of this story.
1275
00:55:02,500 --> 00:55:04,369
Hello, my name is
Erica
1276
00:55:04,435 --> 00:55:05,803
and I hate public speaking,
1277
00:55:05,836 --> 00:55:07,438
but I'm here anyway.
1278
00:55:07,472 --> 00:55:10,775
I am here today to tell
you HSDD is not a figment
1279
00:55:10,808 --> 00:55:12,309
of a woman's imagination.
1280
00:55:12,343 --> 00:55:14,479
It's not a fiction invented
by the drug companies
1281
00:55:14,512 --> 00:55:16,481
and it's not a disease
forced upon women
1282
00:55:16,514 --> 00:55:17,948
by the medical community.
1283
00:55:17,982 --> 00:55:19,517
HSDD is real.
1284
00:55:19,550 --> 00:55:21,352
I know because I had it
1285
00:55:21,386 --> 00:55:22,820
When I was 24 years old
1286
00:55:22,853 --> 00:55:24,855
I was diagnosed
with breast cancer.
1287
00:55:24,889 --> 00:55:25,956
I was clearly informed
1288
00:55:25,990 --> 00:55:28,359
of many of the potential
negative consequences
1289
00:55:28,426 --> 00:55:29,827
of surgical menopause.
1290
00:55:29,860 --> 00:55:32,997
But no one ever advised me
that I was at an increased risk
1291
00:55:33,030 --> 00:55:34,599
for HSDD.
1292
00:55:34,632 --> 00:55:37,368
There was so much
emotion in the room.
1293
00:55:37,402 --> 00:55:40,971
A television doctor suggested
on an interview just last night
1294
00:55:41,005 --> 00:55:43,307
that maybe my libido
is low sometimes
1295
00:55:43,340 --> 00:55:45,209
because I've had a bad day.
1296
00:55:45,242 --> 00:55:47,578
An anchor on a morning
show yesterday said
1297
00:55:47,645 --> 00:55:49,547
that she doesn't need
treatment because a housekeeper
1298
00:55:49,614 --> 00:55:53,017
and time away from the kids
would solve her desire issues.
1299
00:55:53,050 --> 00:55:56,654
If your sexual desire issues
can be cured with a good day
1300
00:55:56,687 --> 00:55:59,056
and a babysitter,
then congratulations,
1301
00:55:59,089 --> 00:56:01,559
you do not have HSDD,
1302
00:56:01,592 --> 00:56:03,561
but the rest of us would
sure appreciate it
1303
00:56:03,594 --> 00:56:05,596
if you would stop
dismissing our concerns
1304
00:56:05,663 --> 00:56:08,132
and making a complete
mockery of the issue.
1305
00:56:10,167 --> 00:56:12,236
Hi, my name is Vicky Loftus.
1306
00:56:12,269 --> 00:56:15,272
I was on the patient
panel in October, 2014
1307
00:56:15,339 --> 00:56:17,675
and told my story
about how HSDD
1308
00:56:17,708 --> 00:56:20,377
has negatively
affected my life.
1309
00:56:20,411 --> 00:56:22,847
My mother was on
the panel as well.
1310
00:56:22,880 --> 00:56:24,682
We both shared our
individual struggles,
1311
00:56:24,715 --> 00:56:26,584
which were sadly
very similar.
1312
00:56:26,651 --> 00:56:28,519
Since my appearance
on the panel,
1313
00:56:28,553 --> 00:56:30,254
my marriage has
suffered greatly.
1314
00:56:30,287 --> 00:56:32,723
So much so that the
conversation of divorce
1315
00:56:32,757 --> 00:56:36,627
is on the table stemming
from my low sexual desire.
1316
00:56:36,694 --> 00:56:38,563
My husband has a difficult
time understanding
1317
00:56:38,596 --> 00:56:40,631
my struggle with
this disorder.
1318
00:56:40,698 --> 00:56:42,900
He still takes my
avoidance of sex personally
1319
00:56:42,933 --> 00:56:45,402
thinking I don't
love him anymore
1320
00:56:45,436 --> 00:56:46,604
and there is something
wrong with him,
1321
00:56:46,637 --> 00:56:48,439
which is farthest
from the truth.
1322
00:56:51,141 --> 00:56:53,444
.
As a mom standing next to your daughter
1323
00:56:53,511 --> 00:56:56,481
who is going through
a divorce at that time,
1324
00:56:56,547 --> 00:57:00,117
for her to get in
front of an FDA panel,
1325
00:57:00,184 --> 00:57:02,720
it took a lot of
courage on her part.
1326
00:57:02,753 --> 00:57:06,791
It was a very traumatic
thing for her.
1327
00:57:06,857 --> 00:57:11,596
So to listen to
those hecklers it,
1328
00:57:11,629 --> 00:57:15,432
it was heartbreaking
to watch that.
1329
00:57:15,466 --> 00:57:16,934
It was just heartbreaking.
1330
00:57:18,669 --> 00:57:21,138
Thank you.
Speaker 31, please.
1331
00:57:21,205 --> 00:57:22,773
There was a woman
who stood up and said,
1332
00:57:22,807 --> 00:57:24,642
let me give you some options:
1333
00:57:26,511 --> 00:57:27,745
read erotica,
1334
00:57:27,778 --> 00:57:29,947
find a different partner,
1335
00:57:29,980 --> 00:57:32,316
get a better shower head.
1336
00:57:32,349 --> 00:57:34,084
.
Here are some things that have helped me with periods
1337
00:57:34,118 --> 00:57:35,653
of low libido:
1338
00:57:37,187 --> 00:57:38,523
switching boyfriends,
1339
00:57:38,589 --> 00:57:40,625
chocolate, coffee,
1340
00:57:40,658 --> 00:57:42,993
certain episodes
of Grey's Anatomy
1341
00:57:43,027 --> 00:57:44,161
pornography,
1342
00:57:44,228 --> 00:57:45,963
upgrading my vibrator,
1343
00:57:45,996 --> 00:57:47,164
reading 50 Shades of Grey,
1344
00:57:47,197 --> 00:57:49,099
a removable shower head,
1345
00:57:49,133 --> 00:57:52,136
and an acceptance of myself
and the libido I came with.
1346
00:57:52,169 --> 00:57:55,172
.
Excuse me, Alexandra, sorry, your two minutes is up.
1347
00:57:56,574 --> 00:57:58,843
.
That's all saying you're doing something wrong
1348
00:57:58,876 --> 00:58:00,645
and it's your fault.
1349
00:58:01,245 --> 00:58:04,148
And you just watched
the faces of women
1350
00:58:04,181 --> 00:58:05,950
who were brave enough
to say the thing
1351
00:58:05,983 --> 00:58:06,984
they were struggling with
1352
00:58:07,017 --> 00:58:11,722
and then others mock them,
be cruel to them.
1353
00:58:11,789 --> 00:58:14,158
And that was hard to watch.
1354
00:58:14,191 --> 00:58:17,595
Sprout's lobbying effort
called Even The Score
1355
00:58:17,628 --> 00:58:22,833
has used deception to mobilize
women with real sexual concerns
1356
00:58:22,867 --> 00:58:25,369
to lobby for their
questionable product.
1357
00:58:25,435 --> 00:58:27,337
They've tried to
distract the public,
1358
00:58:27,371 --> 00:58:28,706
bully the FDA,
1359
00:58:28,773 --> 00:58:32,710
and they have hampered
real sex research.
1360
00:58:32,777 --> 00:58:34,378
But make no mistake,
1361
00:58:34,411 --> 00:58:37,682
Even The Score reveals
the methods and values
1362
00:58:37,715 --> 00:58:39,750
of Sprout Pharmaceuticals.
1363
00:58:39,817 --> 00:58:42,352
Reject this drug
once and for all
1364
00:58:42,386 --> 00:58:44,589
and let's move on to
really help women.
1365
00:58:45,556 --> 00:58:46,523
Thank you.
1366
00:58:46,557 --> 00:58:48,993
Speaker 32, please.
1367
00:58:49,026 --> 00:58:51,729
There was so much politics.
1368
00:58:51,796 --> 00:58:55,165
There was so many people
there angry about the idea
1369
00:58:55,199 --> 00:58:57,835
that a medicine could
help with sexual health.
1370
00:58:57,868 --> 00:58:58,836
If there were clear evidence
1371
00:58:58,869 --> 00:59:00,805
of a clinically
meaningful benefit,
1372
00:59:00,838 --> 00:59:02,740
which I don't
believe there is,
1373
00:59:02,773 --> 00:59:05,275
significant but not
clinically meaningful,
1374
00:59:05,342 --> 00:59:07,712
accompanied by
manageable risks,
1375
00:59:07,745 --> 00:59:09,614
approval might be appropriate.
1376
00:59:09,680 --> 00:59:11,749
Flibanserin is a
mediocre aphrodisiac
1377
00:59:11,782 --> 00:59:13,250
with scary side effects.
1378
00:59:13,317 --> 00:59:16,420
Its effects may be due to
non-specific sedating effects,
1379
00:59:16,453 --> 00:59:19,023
apparently equivalent
to four drinks.
1380
00:59:19,056 --> 00:59:21,258
One of the fears the FDA had
1381
00:59:21,291 --> 00:59:23,728
was that this was
like an aphrodisiac
1382
00:59:23,761 --> 00:59:26,964
and it might be slipped into
somebody's drink in a bar
1383
00:59:27,031 --> 00:59:29,734
and then they'd have
sex with some stranger.
1384
00:59:29,767 --> 00:59:30,901
One thing I worry about is
1385
00:59:30,935 --> 00:59:33,771
because of the
indication of this drug,
1386
00:59:33,838 --> 00:59:40,577
could it be thought of
as like a date rape drug?
1387
00:59:40,611 --> 00:59:43,080
I think that's an
excellent point
1388
00:59:43,113 --> 00:59:47,918
and that is something certainly
that we have thought about.
1389
00:59:47,952 --> 00:59:49,954
But it doesn't work
like that at all.
1390
00:59:50,020 --> 00:59:51,889
Anything that you
have to take daily,
1391
00:59:51,922 --> 00:59:53,724
I will tell you that
1392
00:59:53,758 --> 00:59:56,293
you have to have taken it
for a certain number of days
1393
00:59:56,360 --> 00:59:58,595
before it really has an effect.
1394
00:59:58,629 --> 01:00:00,130
My name is Dr. Irwin Goldstein.
1395
01:00:00,164 --> 01:00:01,866
I serve on
Sprouts Advisory Board.
1396
01:00:01,899 --> 01:00:03,100
And I'm Sue Goldstein.
1397
01:00:03,133 --> 01:00:04,969
We're here for San Diego
Sexual Medicine today,
1398
01:00:05,002 --> 01:00:07,638
and we have no financial
interest in today's outcome.
1399
01:00:07,672 --> 01:00:09,874
.
It was very distressing
1400
01:00:09,907 --> 01:00:12,777
that colleagues
would take this view
1401
01:00:12,810 --> 01:00:14,812
that we were harming people,
1402
01:00:14,879 --> 01:00:17,281
and we had a lot of
evidence that wasn't true.
1403
01:00:17,314 --> 01:00:19,016
It's an embarrassment,
it's a humiliation.
1404
01:00:19,083 --> 01:00:20,918
It's a evil against women.
1405
01:00:20,951 --> 01:00:23,320
It's crazy. It's just crazy.
1406
01:00:23,387 --> 01:00:26,456
To the experts who
do not manage women
1407
01:00:26,490 --> 01:00:27,858
with sexual health problems,
1408
01:00:27,925 --> 01:00:30,661
give these women the
right to choose,
1409
01:00:30,728 --> 01:00:32,963
vote yes to approve,
and thank you.
1410
01:00:32,997 --> 01:00:34,665
.
Thank you.
1411
01:00:34,732 --> 01:00:36,100
.
Some of this, I think,
1412
01:00:36,133 --> 01:00:38,502
is an attempt to
control women,
1413
01:00:38,535 --> 01:00:42,039
and that's been going
on for millennia.
1414
01:00:42,106 --> 01:00:44,141
It's going on now.
1415
01:00:44,174 --> 01:00:47,511
There really is a whole sense
1416
01:00:47,544 --> 01:00:51,048
of not hearing women and
not trying to help them,
1417
01:00:51,115 --> 01:00:54,885
or trying to block something
when help is available.
1418
01:00:54,952 --> 01:00:57,221
And that's
unconscionable to me.
1419
01:01:01,558 --> 01:01:02,827
I'm Dr. Anita Clayton.
1420
01:01:02,860 --> 01:01:05,062
I'm gonna get
straight to the point.
1421
01:01:05,129 --> 01:01:07,998
Stop moving the goalposts.
1422
01:01:08,032 --> 01:01:09,666
The efficacy, safety,
1423
01:01:09,700 --> 01:01:11,836
and clinically meaningful
effects of Flibanserin
1424
01:01:11,869 --> 01:01:13,370
are clear.
1425
01:01:13,403 --> 01:01:16,941
Maybe the message is that you
don't trust women with HSDD,
1426
01:01:18,042 --> 01:01:20,911
or you just don't trust women.
1427
01:01:20,978 --> 01:01:23,714
At the core of this
whole thing was really,
1428
01:01:23,748 --> 01:01:25,282
does it matter?
1429
01:01:25,615 --> 01:01:27,417
And do women deserve.
1430
01:01:27,484 --> 01:01:28,819
I think that's
really what it was.
1431
01:01:28,853 --> 01:01:31,055
Like all this other
was just noise.
1432
01:01:31,121 --> 01:01:34,024
It was just noise to distract
1433
01:01:34,058 --> 01:01:36,226
from the bias at
the centre of it,
1434
01:01:36,260 --> 01:01:37,895
which is, we don't
think it really matters
1435
01:01:37,928 --> 01:01:39,696
if women have a more
satisfying sex life.
1436
01:01:39,730 --> 01:01:41,198
That's the truth.
1437
01:01:41,231 --> 01:01:44,869
We literally heard
this from the FDA
1438
01:01:44,902 --> 01:01:48,906
is that women do not
have to desire sex
1439
01:01:48,939 --> 01:01:50,474
to have sex.
1440
01:01:53,243 --> 01:01:55,179
Yeah.
1441
01:01:55,212 --> 01:01:57,181
.
So with that said,
1442
01:01:57,214 --> 01:02:01,085
we will now turn to
the voting process.
1443
01:02:01,118 --> 01:02:02,987
.
I think about the stakes
1444
01:02:03,020 --> 01:02:05,055
because I knew what
we were up against.
1445
01:02:07,224 --> 01:02:10,727
Ooh. Because we had
done everything we could
1446
01:02:10,761 --> 01:02:12,897
and the team was nervous.
1447
01:02:12,930 --> 01:02:15,933
We felt immense pressure
to win it for women.
1448
01:02:16,000 --> 01:02:17,768
All the women that showed up,
1449
01:02:17,802 --> 01:02:20,037
all the women's health
and rights advocates,
1450
01:02:20,070 --> 01:02:22,773
all the doctors,
1451
01:02:22,807 --> 01:02:24,842
Okay, we ready?
1452
01:02:25,843 --> 01:02:27,878
Okay, let's go.
1453
01:02:30,047 --> 01:02:31,982
.
The emotions are just up and down all day,
1454
01:02:32,049 --> 01:02:35,285
and then they vote sort
of secretly, right?
1455
01:02:35,319 --> 01:02:36,921
They all press a button
1456
01:02:36,954 --> 01:02:39,089
so that they can't
influence each other,
1457
01:02:39,123 --> 01:02:41,158
and the number just
comes up on the screen.
1458
01:02:42,793 --> 01:02:46,897
That process probably
took a minute and a half,
1459
01:02:46,931 --> 01:02:49,733
it felt like twenty minutes
1460
01:02:49,766 --> 01:02:51,902
before that number
came up on the screen,
1461
01:02:51,936 --> 01:02:53,971
and then the room
just erupted.
1462
01:02:59,109 --> 01:03:01,278
* Never believed I
could feel like this
1463
01:03:01,311 --> 01:03:02,980
* Got me feeling so high
1464
01:03:03,047 --> 01:03:07,317
.
The FDA approving the controversial Little Pink Pill.
1465
01:03:07,351 --> 01:03:08,953
.
The FDA approved the new drug
1466
01:03:08,986 --> 01:03:11,421
designed to boost
the female libido.
1467
01:03:11,455 --> 01:03:13,190
* And there ain't
nobody can blame me
1468
01:03:13,257 --> 01:03:15,292
* They can't blame me now
1469
01:03:15,325 --> 01:03:17,494
* 'Cause everything you doing,
yeah that's how I like it
1470
01:03:17,561 --> 01:03:18,695
* You know what
you're doing, yeah *
1471
01:03:18,762 --> 01:03:21,298
.
We got an 18 to six positive vote.
1472
01:03:21,331 --> 01:03:24,034
It just tells you the
strength of the data
1473
01:03:24,101 --> 01:03:26,971
and also the strength of
the people who spoke to say,
1474
01:03:27,004 --> 01:03:29,773
this is meaningful and
I do need this drug.
1475
01:03:33,110 --> 01:03:35,980
.
That day in the room when my hand was shaking
1476
01:03:36,013 --> 01:03:38,148
as the score went up,
1477
01:03:38,182 --> 01:03:39,984
I don't know that the FDA's
ever had a whole room
1478
01:03:40,017 --> 01:03:44,188
erupt into cheers over an
approval of a medication.
1479
01:03:44,221 --> 01:03:46,323
It was so validating.
1480
01:03:46,356 --> 01:03:48,225
And I was on the last
flight out to New York
1481
01:03:48,292 --> 01:03:50,160
to do press the next morning.
1482
01:03:50,194 --> 01:03:53,864
* I hope that you,
you were talkin' 'bout me *
1483
01:03:53,898 --> 01:03:56,500
.
Yesterday science won and so too did women.
1484
01:03:56,533 --> 01:03:58,368
Finally, women have the ability
1485
01:03:58,402 --> 01:04:00,971
to make the choice with
their healthcare providers
1486
01:04:01,005 --> 01:04:02,139
whether or not
they want treatment
1487
01:04:02,172 --> 01:04:05,042
for the most common form of
female sexual dysfunction.
1488
01:04:05,109 --> 01:04:07,978
And it's been a long time
to get to this moment.
1489
01:04:08,012 --> 01:04:10,514
What about the reality
of money raising
1490
01:04:10,547 --> 01:04:13,017
when it comes to
now marketing this,
1491
01:04:13,050 --> 01:04:14,985
and Cind, you're a small
company, privately held.
1492
01:04:15,019 --> 01:04:16,853
We are small, yes.
1493
01:04:16,887 --> 01:04:18,688
How are you going
to pay for all this?
1494
01:04:21,558 --> 01:04:23,327
.
We were the largest news story in the world.
1495
01:04:24,161 --> 01:04:27,898
And then the phone
started ringing.
1496
01:04:27,965 --> 01:04:30,034
In August 2015,
we got the approval.
1497
01:04:31,401 --> 01:04:34,404
Two days later, we sold the
company for a billion dollars.
1498
01:04:41,445 --> 01:04:43,147
*
1499
01:04:43,180 --> 01:04:46,583
.
Up until about 4:00 AM in the morning the night before,
1500
01:04:46,650 --> 01:04:48,385
we were still going
back and forth.
1501
01:04:48,418 --> 01:04:50,587
And I can remember sitting
in the seat at Squawk Box
1502
01:04:50,620 --> 01:04:52,322
next to the CEO,
1503
01:04:52,356 --> 01:04:55,292
and they wanted
confirmation of the signature.
1504
01:04:55,359 --> 01:04:57,561
And they were like 5, 4, 3.
1505
01:04:57,594 --> 01:04:58,662
We got it!
1506
01:04:58,695 --> 01:05:00,897
And it just happened
right there on air.
1507
01:05:00,931 --> 01:05:03,100
To be sure, science
has won the day here.
1508
01:05:03,167 --> 01:05:05,235
So this is a condition that
we've known about medically
1509
01:05:05,269 --> 01:05:06,937
since 1977.
1510
01:05:06,971 --> 01:05:09,106
We have four decades of
medical literature on it.
1511
01:05:09,173 --> 01:05:10,407
The opportunity's quite large.
1512
01:05:10,440 --> 01:05:12,742
You know, and certainly in the
hundreds of millions for us.
1513
01:05:12,776 --> 01:05:14,778
But we're hope, hopefully
it's in the billions
1514
01:05:14,811 --> 01:05:16,580
in terms of, uh,
what this could do
1515
01:05:16,613 --> 01:05:18,782
from a, from a
revenue standpoint,
1516
01:05:18,815 --> 01:05:21,986
.
This whole fight has been about getting women,
1517
01:05:22,052 --> 01:05:22,953
myself included,
1518
01:05:23,020 --> 01:05:26,456
what we deserve and
knowing our worth.
1519
01:05:26,490 --> 01:05:27,624
And I wasn't gonna
take something
1520
01:05:27,657 --> 01:05:29,059
that wasn't what
this was worth.
1521
01:05:29,093 --> 01:05:30,961
Let me ask you about
the Valeant acquisition
1522
01:05:31,028 --> 01:05:33,063
and sort of what
that did for you
1523
01:05:33,097 --> 01:05:36,100
because you've got a lot
more marketing muscle,
1524
01:05:36,133 --> 01:05:38,602
a lot more oomph
behind this product now.
1525
01:05:38,635 --> 01:05:40,470
What kind of a game
changer was that for you?
1526
01:05:40,504 --> 01:05:41,438
Game changer.
1527
01:05:41,471 --> 01:05:43,173
We're a 34 person company
1528
01:05:43,240 --> 01:05:45,475
who managed to get this
across the finish line.
1529
01:05:45,509 --> 01:05:48,412
So this is the ability to make
good on the mission, right?
1530
01:05:48,445 --> 01:05:50,280
This is gonna be
accessible to women
1531
01:05:50,314 --> 01:05:52,782
every corner of the globe
1532
01:05:52,816 --> 01:05:54,784
because we needed
a global player
1533
01:05:54,818 --> 01:05:57,354
to be able to do that in a
way this tiny little company
1534
01:05:57,421 --> 01:05:59,689
with 35 people couldn't do.
1535
01:05:59,756 --> 01:06:02,626
But again, no one
takes you seriously.
1536
01:06:02,659 --> 01:06:05,462
I think this sounds like
a great holiday gift.
1537
01:06:08,732 --> 01:06:10,134
Tonight we'll take a
look at the pros and cons
1538
01:06:10,167 --> 01:06:12,169
of female Viagra.
1539
01:06:13,837 --> 01:06:15,139
.
Pro: When ingested
1540
01:06:15,172 --> 01:06:18,108
Flibanserin increases
a woman's sex drive.
1541
01:06:18,142 --> 01:06:19,809
Con: you might know
it by its old name-
1542
01:06:19,843 --> 01:06:21,311
"wine." Yeah.
1543
01:06:25,349 --> 01:06:27,217
.
The media,
1544
01:06:27,284 --> 01:06:30,154
they picked up on the people
saying "this is dangerous."
1545
01:06:30,187 --> 01:06:31,688
This pill is not for everyone.
1546
01:06:31,721 --> 01:06:33,157
Dizziness four times greater,
1547
01:06:33,190 --> 01:06:35,525
sleepiness, nausea, fatigue.
1548
01:06:35,559 --> 01:06:37,161
There's an interaction
with alcohol.
1549
01:06:37,194 --> 01:06:39,229
.
They splashed it all over
1550
01:06:39,296 --> 01:06:42,699
because they like a story,
they like a conflict
1551
01:06:42,732 --> 01:06:45,169
and it was detrimental.
1552
01:06:45,202 --> 01:06:46,870
But your critics
remain this morning.
1553
01:06:46,903 --> 01:06:48,472
The critics have
not gone away.
1554
01:06:48,505 --> 01:06:50,340
Charlie Rose asked
me like, "Hey Cindy,
1555
01:06:50,374 --> 01:06:52,209
"could you not have invented
a drug with no side effects?"
1556
01:06:52,276 --> 01:06:54,544
.
Is there no way to have created a drug
1557
01:06:54,578 --> 01:06:56,113
without the side effects?
1558
01:06:57,314 --> 01:06:58,715
Uh, no.
1559
01:07:00,217 --> 01:07:02,018
No drug comes
without side effects.
1560
01:07:02,052 --> 01:07:03,887
I think that's very
important, right?
1561
01:07:03,920 --> 01:07:06,256
Addyi is no different than
countless other drugs.
1562
01:07:06,323 --> 01:07:09,025
It was so obtuse.
1563
01:07:09,059 --> 01:07:11,228
Again, you can't have any risk
1564
01:07:11,261 --> 01:07:13,097
'cause this thing
doesn't really matter.
1565
01:07:13,563 --> 01:07:16,866
The challenge with this
drug is that it is limited
1566
01:07:16,900 --> 01:07:20,870
to a very strict
subpopulation of women
1567
01:07:20,904 --> 01:07:24,674
who have a sudden or
new onset of low desire
1568
01:07:24,708 --> 01:07:26,510
and no other explanations.
1569
01:07:26,543 --> 01:07:29,146
And it's a reproductive
age population too,
1570
01:07:29,179 --> 01:07:31,348
and we should be thinking
about and concerned about
1571
01:07:31,381 --> 01:07:34,017
the reproductive
safety of this drug.
1572
01:07:34,050 --> 01:07:37,354
It just shows up over
and over and over again.
1573
01:07:37,387 --> 01:07:40,257
.
The Addyi comes with a black box warning from the FDA,
1574
01:07:40,324 --> 01:07:41,758
the strongest
warning it can give
1575
01:07:41,791 --> 01:07:44,094
because it's loaded
with side effects.
1576
01:07:44,128 --> 01:07:50,234
A box warning literally is a
box in the medical information.
1577
01:07:50,267 --> 01:07:53,103
They said you couldn't
drink alcohol at all.
1578
01:07:53,137 --> 01:07:57,607
And their warning for Viagra
was you shouldn't take it,
1579
01:07:57,641 --> 01:08:00,110
not that you couldn't,
but you shouldn't take it.
1580
01:08:00,177 --> 01:08:03,380
So putting something
in a boxed warning
1581
01:08:03,413 --> 01:08:07,417
that is not a legitimate
safety issue is a real problem.
1582
01:08:08,885 --> 01:08:11,421
.
Doctors had to take a test to write it.
1583
01:08:11,455 --> 01:08:13,290
Pharmacists had to take
a test to dispense it
1584
01:08:13,357 --> 01:08:14,958
and women had to sign
a piece of paper
1585
01:08:15,024 --> 01:08:17,794
promising they wouldn't
drink if they were on it.
1586
01:08:17,827 --> 01:08:21,131
.
They put it in a classification with things
1587
01:08:21,165 --> 01:08:23,099
that are very harmful,
1588
01:08:23,133 --> 01:08:25,602
and Addyi is not harmful.
1589
01:08:25,635 --> 01:08:26,770
I took alcohol,
1590
01:08:26,803 --> 01:08:28,472
I didn't, I
wasn't even told
1591
01:08:28,538 --> 01:08:30,407
that I couldn't
take alcohol.
1592
01:08:30,440 --> 01:08:34,110
And everybody that I know
had a drink before dinner.
1593
01:08:34,144 --> 01:08:36,012
You take this
medication at night,
1594
01:08:36,079 --> 01:08:38,282
you're not supposed to get
behind the wheel of a car
1595
01:08:38,315 --> 01:08:39,883
or take it in the morning.
1596
01:08:40,484 --> 01:08:43,287
.
The other thing is that men can take it from
1597
01:08:43,320 --> 01:08:45,322
basically any age,
1598
01:08:45,355 --> 01:08:49,993
and that includes people
up to 70, 80, or whatever.
1599
01:08:50,026 --> 01:08:53,363
Women though had
to be between 18
1600
01:08:53,430 --> 01:08:56,633
and where they entered
the perimenopause.
1601
01:08:56,666 --> 01:09:01,171
So there's real problems
there in a discrepancy
1602
01:09:01,238 --> 01:09:03,873
between men and women.
1603
01:09:03,940 --> 01:09:06,776
And there was a very
paternalistic attitude.
1604
01:09:06,810 --> 01:09:09,979
.
Addyi is not approved for use in postmenopausal women.
1605
01:09:10,013 --> 01:09:11,781
The FDA says more
studies are needed
1606
01:09:11,815 --> 01:09:14,484
to determine whether it's
safe and effective for them.
1607
01:09:14,518 --> 01:09:18,988
.
They just made it impossible to get the drug.
1608
01:09:19,022 --> 01:09:22,359
And with all the restrictions
on the pharmacists,
1609
01:09:22,426 --> 01:09:23,960
they weren't selling it.
1610
01:09:24,661 --> 01:09:27,197
.
It's been on the market now for three or four weeks
1611
01:09:27,231 --> 01:09:31,535
and the demands so far has been
really, really, really low.
1612
01:09:31,601 --> 01:09:32,669
And frankly, you know,
1613
01:09:32,702 --> 01:09:34,704
Valeant been in the news
for a lot of other reasons
1614
01:09:34,738 --> 01:09:36,573
for some of the troubles
that they've had.
1615
01:09:38,208 --> 01:09:43,012
.
For Valeant to jack the price up the way they did
1616
01:09:43,046 --> 01:09:45,249
is I think criminal for women.
1617
01:09:46,383 --> 01:09:48,518
.
Valeant's a very controversial company.
1618
01:09:48,552 --> 01:09:50,587
A lot of stuff came out
about its business model,
1619
01:09:50,654 --> 01:09:53,490
particularly the business model
of buying other drug companies
1620
01:09:53,523 --> 01:09:56,360
then jacking up the
prices of those drugs.
1621
01:09:56,393 --> 01:09:58,662
Well then it was
cost prohibitive,
1622
01:09:58,695 --> 01:10:00,497
so they stopped taking it.
1623
01:10:02,165 --> 01:10:03,733
And that was the end of it.
1624
01:10:07,103 --> 01:10:08,338
.
And then, of course,
1625
01:10:08,372 --> 01:10:10,407
the next thing that happened
is they shelved it.
1626
01:10:18,448 --> 01:10:20,917
The intention was
I was gonna stay.
1627
01:10:20,984 --> 01:10:22,252
You know, that was
part of the deal.
1628
01:10:22,286 --> 01:10:25,589
I would stay and build their
entire women's health franchise,
1629
01:10:25,655 --> 01:10:28,558
and within three months
of that deal closing,
1630
01:10:28,592 --> 01:10:31,595
I got a phone call that
invited me to leave.
1631
01:10:31,661 --> 01:10:32,962
And not long after that,
1632
01:10:33,029 --> 01:10:34,831
they got rid of
the entire team.
1633
01:10:37,133 --> 01:10:39,969
I've never been more depressed
in my life than that period.
1634
01:10:41,505 --> 01:10:45,642
To have won one and then
them to not launch it,
1635
01:10:45,709 --> 01:10:48,612
and the women who had
shown up at those meetings
1636
01:10:48,645 --> 01:10:50,447
to not be able to get it.
1637
01:10:51,415 --> 01:10:56,085
That felt the
worst of anything.
1638
01:10:56,119 --> 01:10:58,955
It was, it was,
that was brutal for me.
1639
01:10:58,988 --> 01:11:02,392
.
Women that are struggling with HSDD should have the option
1640
01:11:02,426 --> 01:11:04,093
to choose a safe and
approved treatment
1641
01:11:04,127 --> 01:11:06,296
with guidance from their
healthcare provider.
1642
01:11:06,330 --> 01:11:07,731
Thank you.
1643
01:11:08,131 --> 01:11:11,501
.
How can you possibly pass something
1644
01:11:11,568 --> 01:11:13,937
that is so
wonderful for women
1645
01:11:13,970 --> 01:11:16,139
and then have it ripped out?
1646
01:11:16,172 --> 01:11:18,274
After all of this work,
1647
01:11:18,308 --> 01:11:23,112
and after all of this emotion,
1648
01:11:23,146 --> 01:11:26,950
we're down to square one
again and we still are.
1649
01:11:29,753 --> 01:11:32,021
.
We just got new metrics in,
1650
01:11:32,088 --> 01:11:33,790
Donald J. Trump
1651
01:11:33,823 --> 01:11:38,328
is the President of the
United States Elect.
1652
01:11:38,362 --> 01:11:42,332
.
The past five to ten years really calls into question
1653
01:11:42,366 --> 01:11:45,201
where the state of
women's health is going.
1654
01:11:49,205 --> 01:11:51,708
.
The last year has been incredibly difficult for women.
1655
01:11:51,775 --> 01:11:54,478
We have seen major
attacks on Obamacare,
1656
01:11:54,511 --> 01:11:55,979
protections for birth control.
1657
01:11:56,012 --> 01:11:57,647
And we know that
on the state level
1658
01:11:57,681 --> 01:11:58,748
there are a number of courts
1659
01:11:58,782 --> 01:12:01,385
that are working to roll
back our right to choose.
1660
01:12:03,787 --> 01:12:06,656
.
Tonight we remember an American icon,
1661
01:12:06,690 --> 01:12:08,692
Supreme Court Justice
Ruth Bader Ginsburg
1662
01:12:08,758 --> 01:12:10,394
died today.
1663
01:12:10,460 --> 01:12:12,696
.
Ginsburg was seen as a champion of women's rights.
1664
01:12:12,762 --> 01:12:14,564
Her passing now gives
President Donald Trump
1665
01:12:14,631 --> 01:12:17,501
the chance to shore up the
conservative majority
1666
01:12:17,534 --> 01:12:19,135
when choosing a replacement.
1667
01:12:19,736 --> 01:12:21,871
.
Confirmation brings a major shift to the court
1668
01:12:21,905 --> 01:12:24,408
and it will have an
impact for years to come.
1669
01:12:27,210 --> 01:12:30,647
.
One of the tipping points in the conversation that we're having
1670
01:12:30,680 --> 01:12:35,752
requires us to look back to what
happened just a few years ago
1671
01:12:35,819 --> 01:12:38,522
with the overturning
of Roe v. Wade.
1672
01:12:38,555 --> 01:12:41,691
I don't accept this ruling!
We're not going to go back!
1673
01:12:41,725 --> 01:12:43,560
What changed since 1973?
1674
01:12:43,593 --> 01:12:45,261
What changed?
1675
01:12:46,229 --> 01:12:48,197
.
To be at a time in my life
1676
01:12:48,231 --> 01:12:49,899
that the rights
that my generation
1677
01:12:49,933 --> 01:12:52,068
fought so hard to have
1678
01:12:52,101 --> 01:12:54,638
see them taken away.
1679
01:12:54,671 --> 01:12:59,242
What right does anybody have
to say what I do with my body?
1680
01:12:59,308 --> 01:13:02,512
Why does any right
and men have a right to,
1681
01:13:02,546 --> 01:13:04,414
to, to control any of that,
1682
01:13:04,448 --> 01:13:06,883
whether it's sexual health,
reproductive rights, uh,
1683
01:13:06,916 --> 01:13:09,453
who, who you're married to,
1684
01:13:09,519 --> 01:13:11,387
none of that is
anybody's business
1685
01:13:11,421 --> 01:13:12,889
if you're not harming
anybody else,
1686
01:13:12,922 --> 01:13:14,591
and I will stand up and
support and hope to God,
1687
01:13:14,658 --> 01:13:17,594
like I have two
granddaughters, teenagers.
1688
01:13:17,627 --> 01:13:19,262
I hope that they live
in a world better
1689
01:13:19,328 --> 01:13:21,197
than the world we're
looking at today.
1690
01:13:22,165 --> 01:13:24,734
.
Today the story of Josseli Barnica,
1691
01:13:24,768 --> 01:13:27,571
a young mother pregnant
with her second child
1692
01:13:27,604 --> 01:13:30,607
who died of sepsis
just one week
1693
01:13:30,640 --> 01:13:33,610
after Texas's abortion
ban went into effect.
1694
01:13:33,643 --> 01:13:37,714
Despite being diagnosed with
a miscarriage in progress,
1695
01:13:37,747 --> 01:13:39,583
doctors said they
could not treat her,
1696
01:13:39,616 --> 01:13:41,485
meaning provide an abortion,
1697
01:13:41,551 --> 01:13:44,488
until her fetus no
longer had a heartbeat.
1698
01:13:44,554 --> 01:13:46,289
.
People are literally dying
1699
01:13:46,322 --> 01:13:49,559
as a result of these
horrible political changes.
1700
01:13:49,593 --> 01:13:51,394
We have to get all of
this reversed back
1701
01:13:51,427 --> 01:13:53,062
to the where it once was,
1702
01:13:53,096 --> 01:13:54,631
where-where people
have rights.
1703
01:13:54,698 --> 01:13:56,132
And-and reproductive
and sexual rights
1704
01:13:56,165 --> 01:13:58,735
are just as important
as cardiac rights,
1705
01:13:58,768 --> 01:14:01,471
as orthopedic rights,
as any other right.
1706
01:14:01,538 --> 01:14:02,939
I'm scared to have a daughter
1707
01:14:02,972 --> 01:14:06,943
because I don't know how the
world is going to treat her,
1708
01:14:06,976 --> 01:14:08,645
'cause you could be the
best parent in the world
1709
01:14:08,712 --> 01:14:10,514
and you could teach that girl
1710
01:14:10,580 --> 01:14:14,283
to be the strongest
possible person,
1711
01:14:14,317 --> 01:14:17,186
but you have no idea when
she goes out into the world
1712
01:14:17,253 --> 01:14:19,656
how the world is gonna
receive and treat her.
1713
01:14:19,723 --> 01:14:23,493
It's also a scary time
with what is happening
1714
01:14:23,560 --> 01:14:26,630
to traditionally
marginalized groups.
1715
01:14:27,497 --> 01:14:30,333
Trans people are the most
marginalized in our society
1716
01:14:30,399 --> 01:14:34,671
and they've been
scapegoated in a way that
1717
01:14:34,704 --> 01:14:38,608
they are sort of being used as
this smoke and mirrors vehicle
1718
01:14:38,642 --> 01:14:41,611
in this all out assault
on personal autonomy.
1719
01:14:41,645 --> 01:14:43,980
And it's scary how quickly
that has escalated.
1720
01:14:44,013 --> 01:14:46,783
You know, back in the
twenty late teens,
1721
01:14:46,816 --> 01:14:49,152
it was this discussion
around bathrooms
1722
01:14:49,185 --> 01:14:52,021
and then very quickly it
was trans people in sports.
1723
01:14:52,055 --> 01:14:54,223
It is a hot topic in
American politics,
1724
01:14:54,290 --> 01:14:55,859
whether or not
transgender people
1725
01:14:55,892 --> 01:14:58,862
can compete in categories
in which they identify.
1726
01:14:58,928 --> 01:15:00,797
.
And then very quickly it was
1727
01:15:00,830 --> 01:15:02,465
trying to ban care
for trans youth,
1728
01:15:02,498 --> 01:15:04,000
and now there's multiple
states actually trying to
1729
01:15:04,033 --> 01:15:06,536
limit care for trans adults.
1730
01:15:06,570 --> 01:15:09,739
So what happened with
Roe is a direct extension
1731
01:15:09,806 --> 01:15:12,709
of what's been happening
with trans rights.
1732
01:15:12,776 --> 01:15:13,843
At the end of the day,
1733
01:15:13,877 --> 01:15:16,179
if like we collectively
as-as a society
1734
01:15:16,212 --> 01:15:19,182
are not standing up and
protecting trans rights,
1735
01:15:19,215 --> 01:15:21,184
then we're not
protecting our rights.
1736
01:15:21,217 --> 01:15:25,989
Regardless of what's going on
in Washington politically,
1737
01:15:26,022 --> 01:15:27,791
people are still suffering.
1738
01:15:27,824 --> 01:15:29,726
So all the games that
people are playing,
1739
01:15:29,793 --> 01:15:32,696
all the rights that are
being stripped from people
1740
01:15:32,729 --> 01:15:34,898
regardless of who they are,
1741
01:15:34,964 --> 01:15:36,532
at the end of the day,
1742
01:15:36,566 --> 01:15:38,735
my patient in my room
is still suffering
1743
01:15:38,802 --> 01:15:41,537
because I will be honest right
now as a gynecologist,
1744
01:15:41,571 --> 01:15:43,039
it's a little bleak.
1745
01:15:43,072 --> 01:15:44,373
Patients are feeling it too
1746
01:15:44,407 --> 01:15:46,776
when they come into
the exam room as well.
1747
01:15:46,843 --> 01:15:48,745
If our reproductive rights,
1748
01:15:48,778 --> 01:15:51,547
our rights to bodily
autonomy are threatened,
1749
01:15:51,581 --> 01:15:54,383
we almost can't even get to
the conversation of pleasure
1750
01:15:54,417 --> 01:15:57,721
because we're fighting
for basic human rights,
1751
01:15:57,754 --> 01:15:59,989
those fundamental
rights to exist
1752
01:16:00,023 --> 01:16:01,758
to have control
over our bodies.
1753
01:16:01,791 --> 01:16:03,593
And that's very scary.
1754
01:16:03,827 --> 01:16:07,363
But I don't wanna lose the
conversation around pleasure
1755
01:16:07,396 --> 01:16:09,933
as we focus on rights itself
1756
01:16:09,999 --> 01:16:11,234
because pleasure
is a part of that.
1757
01:16:11,267 --> 01:16:15,404
And in fact, if we focus on
everybody's right to pleasure,
1758
01:16:15,438 --> 01:16:17,306
men, women,
folks of all genders,
1759
01:16:17,373 --> 01:16:19,275
if we talk about pleasure,
1760
01:16:19,308 --> 01:16:24,247
then we have more support
to talk about rights.
1761
01:16:24,280 --> 01:16:26,215
And I think that they
go hand in hand.
1762
01:16:26,249 --> 01:16:27,450
.
You need people yelling and screaming,
1763
01:16:27,516 --> 01:16:28,752
and you need coalitions,
1764
01:16:28,785 --> 01:16:30,319
and you need
people getting loud.
1765
01:16:30,386 --> 01:16:31,287
You need advocacy,
1766
01:16:31,354 --> 01:16:33,122
you need research,
you need mentorship,
1767
01:16:33,156 --> 01:16:34,824
you need awareness,
you need communicat-
1768
01:16:34,891 --> 01:16:36,125
You need all of those things.
1769
01:16:36,159 --> 01:16:38,928
.
We need a seat at the medical school tables.
1770
01:16:38,962 --> 01:16:40,229
Who's coming up with
the curriculum?
1771
01:16:40,263 --> 01:16:43,266
How many hours need to be
devoted to this subject?
1772
01:16:43,299 --> 01:16:45,769
We need a seat at
the FDA in terms of
1773
01:16:45,802 --> 01:16:47,837
what medications are
getting FDA approved.
1774
01:16:47,904 --> 01:16:50,473
What roadblocks are they
putting up in place
1775
01:16:50,539 --> 01:16:52,809
trying to protect women
and keep us safe,
1776
01:16:52,842 --> 01:16:55,679
which actually just create
huge barriers to care.
1777
01:16:55,745 --> 01:16:58,815
We need to hold insurance
companies responsible.
1778
01:16:58,848 --> 01:17:00,616
And our patients
need to speak up
1779
01:17:00,650 --> 01:17:02,919
and demand from
their congressmen,
1780
01:17:02,952 --> 01:17:04,053
from their legislators
1781
01:17:04,087 --> 01:17:06,222
that these are important
issues that they deserve.
1782
01:17:07,556 --> 01:17:09,926
.
The most important way
1783
01:17:09,959 --> 01:17:11,494
in which any individual
1784
01:17:11,527 --> 01:17:16,132
could make an impact on this
fight for bodily autonomy
1785
01:17:16,165 --> 01:17:18,835
and the right to
equal amounts of care,
1786
01:17:18,868 --> 01:17:22,672
would be to educate ourselves
and to remain curious.
1787
01:17:22,706 --> 01:17:26,475
And when we hear something that
doesn't quite seem the same
1788
01:17:26,509 --> 01:17:28,611
as what we were
trained to think,
1789
01:17:28,644 --> 01:17:30,814
to push back a little bit
1790
01:17:30,847 --> 01:17:33,950
and realize that the truth
is actually something
1791
01:17:33,983 --> 01:17:36,485
that's been hidden from
us for a very long time.
1792
01:17:36,519 --> 01:17:38,922
.
I think the key is to not be discouraged by the losses.
1793
01:17:39,923 --> 01:17:43,359
There will be losses and you
can't just take that and go,
1794
01:17:43,426 --> 01:17:45,328
well there's no point
in fighting this fight
1795
01:17:45,361 --> 01:17:46,830
'cause we just lost that fight.
1796
01:17:46,863 --> 01:17:48,497
And I think right now
that's what we have to do,
1797
01:17:48,531 --> 01:17:51,701
is we keep having to
push for the right answer.
1798
01:18:00,043 --> 01:18:07,917
*
1799
01:18:07,984 --> 01:18:10,920
.
In the dark days after the CEO fired me,
1800
01:18:10,987 --> 01:18:12,856
no one was feeling
sorry for me, right?
1801
01:18:12,889 --> 01:18:15,358
I had really the
entrepreneur's dream come true.
1802
01:18:15,391 --> 01:18:16,692
I exited the business.
1803
01:18:16,726 --> 01:18:19,228
It was an incredible outcome
for all the shareholders,
1804
01:18:19,262 --> 01:18:23,232
and yet I found myself
really unfulfilled
1805
01:18:23,266 --> 01:18:25,334
because it's not what
I'd set out to do.
1806
01:18:25,368 --> 01:18:27,403
.
Well the drama isn't over for the drug maker,
1807
01:18:27,436 --> 01:18:28,704
Valeant Pharmaceuticals,
1808
01:18:28,738 --> 01:18:33,042
the CEO just recently back
from medical leave is now out.
1809
01:18:33,076 --> 01:18:34,543
.
So when the new CEO came,
1810
01:18:34,577 --> 01:18:36,913
I asked him if he'd have
breakfast with me in New York
1811
01:18:36,980 --> 01:18:39,348
and I sat down with him
and I said, "Give it back."
1812
01:18:39,382 --> 01:18:41,184
He said, "No thank you.
Go away."
1813
01:18:42,819 --> 01:18:45,388
So I issued a lawsuit.
1814
01:18:45,421 --> 01:18:47,891
They'd made commitments to
me on what they would do.
1815
01:18:47,924 --> 01:18:50,960
You know, how much they would
put toward the marketing,
1816
01:18:51,027 --> 01:18:52,929
the education of
physicians on it.
1817
01:18:52,996 --> 01:18:55,899
And they were in breach
of all those obligations.
1818
01:18:55,932 --> 01:18:58,902
And ultimately in exchange
for dropping the lawsuit,
1819
01:18:58,935 --> 01:19:00,469
they gave the product back.
1820
01:19:00,503 --> 01:19:04,407
Just give us the history
of this female Viagra drug
1821
01:19:04,440 --> 01:19:05,474
because it was bought,
wasn't it,
1822
01:19:05,508 --> 01:19:07,777
by Valeant and
went nowhere fast.
1823
01:19:07,811 --> 01:19:09,278
And now she's bought it back.
1824
01:19:09,312 --> 01:19:12,782
.
Yeah, Cindy successfully settled with Valeant a lawsuit
1825
01:19:12,816 --> 01:19:15,318
that allowed them to get the
drug back at no cost to them.
1826
01:19:15,351 --> 01:19:17,286
And they're taking this
back to the market
1827
01:19:17,320 --> 01:19:18,822
for the second time.
1828
01:19:18,855 --> 01:19:21,858
And so it's basically the,
the drug's second shot.
1829
01:19:25,594 --> 01:19:26,762
.
The minute we got it back,
1830
01:19:26,796 --> 01:19:27,997
we went to back to work
1831
01:19:28,064 --> 01:19:30,499
and we invested all of
these dollars back into
1832
01:19:30,566 --> 01:19:32,335
all the scenarios that we
could show back up to the FDA
1833
01:19:32,368 --> 01:19:35,638
and actually got that black
box warning contraindication
1834
01:19:35,671 --> 01:19:36,806
removed.
1835
01:19:36,840 --> 01:19:39,108
It has an entirely
different label today.
1836
01:19:39,142 --> 01:19:42,178
No doctor has to take a
test to prescribe it.
1837
01:19:42,211 --> 01:19:46,349
Eli does what he calls pharma
or farm P-H-A-R-M to table.
1838
01:19:46,382 --> 01:19:47,483
That's right.
1839
01:19:47,516 --> 01:19:49,986
So he's making sure all
these pills are coming off
1840
01:19:50,019 --> 01:19:52,655
the manufacturing line.
1841
01:19:52,688 --> 01:19:54,323
Kristen, our chief of staff,
1842
01:19:54,357 --> 01:19:57,493
Margaret in finance here.
1843
01:19:57,526 --> 01:20:01,831
Chrissy Newbauer, who runs
customer service for us.
1844
01:20:01,865 --> 01:20:05,034
Michelle, who's working in
customer service as well.
1845
01:20:05,068 --> 01:20:06,002
When we got approved,
1846
01:20:06,035 --> 01:20:09,005
we were confined to only
premenopausal women.
1847
01:20:09,038 --> 01:20:14,143
So we've submitted for our
postmenopausal expansion of use.
1848
01:20:14,543 --> 01:20:15,478
.
I don't even like to say
1849
01:20:15,511 --> 01:20:17,881
that we've submitted
for postmenopausal.
1850
01:20:17,914 --> 01:20:21,851
We've submitted for approval
in women with HSDD.
1851
01:20:21,885 --> 01:20:24,687
It, it's not for approval of
postmenopausal women, right?
1852
01:20:24,720 --> 01:20:25,889
It's women with HSDD
1853
01:20:25,955 --> 01:20:27,823
'cause that's who it should
always have been approved for.
1854
01:20:27,857 --> 01:20:29,058
And so,
1855
01:20:29,092 --> 01:20:32,361
after we disprove the
alcohol contraindication,
1856
01:20:32,395 --> 01:20:35,031
if you Google
Addyi and alcohol,
1857
01:20:35,064 --> 01:20:39,202
what comes up is Addyi is
contraindicated with alcohol.
1858
01:20:39,235 --> 01:20:41,570
That's still out there,
that narrative.
1859
01:20:41,637 --> 01:20:44,373
Like even though
we proved it,
1860
01:20:44,407 --> 01:20:47,210
that narrative, six years,
is still out there,
1861
01:20:47,243 --> 01:20:48,844
and it's still
out there in part
1862
01:20:48,878 --> 01:20:50,880
because FDA keeps
it out there.
1863
01:20:50,914 --> 01:20:53,249
So the first order of
business was science,
1864
01:20:53,282 --> 01:20:55,418
and then I think the
second order of business
1865
01:20:55,451 --> 01:20:59,522
has been demystifying
all of the garbage
1866
01:20:59,555 --> 01:21:01,524
that's been out
there about this.
1867
01:21:01,557 --> 01:21:02,525
Women are like,
1868
01:21:02,558 --> 01:21:04,393
what do you mean there's
a pink pill for me?
1869
01:21:04,427 --> 01:21:05,561
I've never heard of it.
1870
01:21:05,594 --> 01:21:08,431
And that is now
the real problem.
1871
01:21:08,464 --> 01:21:09,398
You guys know
1872
01:21:09,432 --> 01:21:11,600
that I've been fighting
for years on this issue,
1873
01:21:11,634 --> 01:21:15,404
that I fought to get the first
FDA approved treatment option
1874
01:21:15,438 --> 01:21:16,739
for women's libido.
1875
01:21:16,772 --> 01:21:18,975
All the while hearing
the same excuse,
1876
01:21:19,042 --> 01:21:21,744
"Mmm, women's libido
is complicated."
1877
01:21:21,777 --> 01:21:24,613
Is it complicated or is
it just not prioritized?
1878
01:21:24,647 --> 01:21:26,415
I had nothing on social media,
1879
01:21:26,449 --> 01:21:27,450
but you know what?
1880
01:21:27,483 --> 01:21:29,252
Somebody had to speak up
1881
01:21:29,285 --> 01:21:32,555
and once I spoke up,
it just never stopped.
1882
01:21:32,588 --> 01:21:34,790
When doctors
dismiss our pain,
1883
01:21:34,857 --> 01:21:35,925
downplay our symptoms,
1884
01:21:35,959 --> 01:21:38,161
or essentially tell us
it's all in your head,
1885
01:21:38,227 --> 01:21:40,229
we learn to be our
own advocates.
1886
01:21:40,263 --> 01:21:42,765
That's not empowerment,
that's survival.
1887
01:21:42,798 --> 01:21:43,799
Cindy, welcome to the show.
1888
01:21:43,832 --> 01:21:44,968
Thanks for having me.
1889
01:21:45,001 --> 01:21:46,469
The truth is, I knew that
you were gonna be wearing
1890
01:21:46,502 --> 01:21:47,470
pink today.
1891
01:21:47,503 --> 01:21:48,737
I know, it's shocking.
1892
01:21:48,771 --> 01:21:51,474
I think Addyi has parallels to
all of these other conversations
1893
01:21:51,507 --> 01:21:53,109
we're having right now
1894
01:21:53,142 --> 01:21:55,611
that I'd like to think
we've had a hand in
1895
01:21:55,644 --> 01:21:58,414
because when you fight back,
you can win.
1896
01:22:02,318 --> 01:22:03,419
Dr. Blair Peters here,
1897
01:22:03,452 --> 01:22:04,620
full-time gender
affirming surgeon.
1898
01:22:04,653 --> 01:22:05,754
Hi everybody, uh,
1899
01:22:05,788 --> 01:22:07,957
Rachel Rubin, urologist
and sexual medicine specialist.
1900
01:22:07,991 --> 01:22:09,658
We're live on
Instagram right now.
1901
01:22:09,725 --> 01:22:11,827
* I don't want to
want when I wanna
1902
01:22:11,894 --> 01:22:14,330
* Anything I want cuz
I like it like that *
1903
01:22:14,397 --> 01:22:15,464
.
So this person asked,
1904
01:22:15,498 --> 01:22:18,667
I pee after sex and yet
I'm still getting UTIs.
1905
01:22:18,701 --> 01:22:19,902
What am I doing wrong?
1906
01:22:19,935 --> 01:22:21,971
Just wanted to give you guys
a walkthrough to this device.
1907
01:22:22,005 --> 01:22:24,173
Um, it is for
erectile dysfunction.
1908
01:22:24,207 --> 01:22:26,509
Here are things I would do
to have a better sex life.
1909
01:22:26,542 --> 01:22:27,710
.
It is so fun
1910
01:22:27,776 --> 01:22:32,348
to watch these badass
younger physicians.
1911
01:22:32,415 --> 01:22:34,350
Hi everybody,
it's your education share,
1912
01:22:34,417 --> 01:22:35,851
Sarah Cigna.
1913
01:22:35,884 --> 01:22:38,487
.
Whether they're on Instagram breaking barriers
1914
01:22:38,521 --> 01:22:42,825
or they're in the room
challenging conventional wisdom,
1915
01:22:42,858 --> 01:22:43,892
I love it.
1916
01:22:43,959 --> 01:22:45,761
* I'm a rebel *
1917
01:22:46,229 --> 01:22:48,831
* I'm a rebel
1918
01:22:48,864 --> 01:22:50,399
I am not a magician,
1919
01:22:50,466 --> 01:22:53,702
but my batting average
is really fricking good.
1920
01:22:53,736 --> 01:22:56,505
And in our practice
we take a lot of time
1921
01:22:56,539 --> 01:22:57,673
to get to know you,
1922
01:22:57,706 --> 01:22:59,542
to figure out what's
bothering you,
1923
01:22:59,575 --> 01:23:02,378
and to figure out how do we
optimize your quality of life.
1924
01:23:02,445 --> 01:23:04,547
Stacey, David,
it's great to see ya!
1925
01:23:04,580 --> 01:23:05,514
Good to see you.
1926
01:23:05,548 --> 01:23:07,783
One of the things we
often ask people is,
1927
01:23:07,816 --> 01:23:10,219
what does sex look like
for you right now?
1928
01:23:10,253 --> 01:23:12,721
And compare that to what
you want it to look like.
1929
01:23:12,755 --> 01:23:13,856
Why is that important?
1930
01:23:13,889 --> 01:23:17,026
Because I can't assume what
kind of sex you're having
1931
01:23:17,060 --> 01:23:19,028
or even what you want
it to look like,
1932
01:23:19,062 --> 01:23:22,031
and the more I understand
you and what your goals are,
1933
01:23:22,065 --> 01:23:23,266
then we see magic.
1934
01:23:23,332 --> 01:23:25,534
When you really take
the time with people,
1935
01:23:25,568 --> 01:23:27,203
that's when the magic happens.
1936
01:23:27,236 --> 01:23:29,004
That's why I think
it is so important
1937
01:23:29,038 --> 01:23:31,407
during an annual exam
to encourage women
1938
01:23:31,440 --> 01:23:33,109
to hold a hand mirror
1939
01:23:33,176 --> 01:23:35,278
while I go through their
external vulvar exam.
1940
01:23:35,344 --> 01:23:36,912
I feel like most of the
time when I do that
1941
01:23:36,945 --> 01:23:39,582
women are so
shocked and happy
1942
01:23:39,615 --> 01:23:41,084
that somebody took
the time to show them
1943
01:23:41,150 --> 01:23:43,419
really who they
are down there.
1944
01:23:43,486 --> 01:23:47,356
And that's just one step in
the process of empowering women
1945
01:23:47,390 --> 01:23:50,526
to take more ownership over
their own sexual function.
1946
01:23:50,559 --> 01:23:52,928
.
Patients and we as clinicians,
1947
01:23:52,961 --> 01:23:54,697
need some sense of community,
1948
01:23:54,730 --> 01:23:57,266
especially in the current
political climate.
1949
01:23:57,333 --> 01:23:59,735
Without people who
are banding together,
1950
01:23:59,768 --> 01:24:00,936
creating community,
1951
01:24:01,003 --> 01:24:02,905
creating safe spaces,
1952
01:24:02,938 --> 01:24:05,908
and pushing the needle forward,
1953
01:24:05,941 --> 01:24:08,277
we're never gonna get anywhere.
1954
01:24:08,344 --> 01:24:11,114
.
We should be able to stand up for our rights
1955
01:24:11,147 --> 01:24:12,348
and say, "I want more."
1956
01:24:12,381 --> 01:24:14,250
I want something better
out of this relationship.
1957
01:24:14,283 --> 01:24:15,751
I want something
better outta sex.
1958
01:24:15,784 --> 01:24:17,953
I want something
better out of my job.
1959
01:24:17,986 --> 01:24:19,322
I want something
better from, you know,
1960
01:24:19,388 --> 01:24:21,290
from the, from my family,
1961
01:24:21,357 --> 01:24:24,593
but you, but if you
don't tell somebody,
1962
01:24:24,627 --> 01:24:27,230
then how can you expect
somebody else to help you?
1963
01:24:27,263 --> 01:24:30,433
.
The underlying theme of whether it's sexual health
1964
01:24:30,466 --> 01:24:32,735
to reproductive
health is choice.
1965
01:24:32,768 --> 01:24:34,303
So whether it's
having an orgasm
1966
01:24:34,337 --> 01:24:35,638
or having an abortion,
1967
01:24:35,671 --> 01:24:37,640
women should have the
ability to choose
1968
01:24:37,673 --> 01:24:40,443
what is the best
thing for them.
1969
01:24:40,476 --> 01:24:41,944
.
A lot of the culture in medicine
1970
01:24:41,977 --> 01:24:43,812
is still very anti
speaking out
1971
01:24:43,879 --> 01:24:47,616
and it's because we don't
speak up for things
1972
01:24:47,650 --> 01:24:50,153
that the narrative has
become very warped
1973
01:24:50,186 --> 01:24:53,156
and very much straight
away from science.
1974
01:24:53,222 --> 01:24:55,458
So I think there's a huge
need more than ever
1975
01:24:55,491 --> 01:24:58,161
for a lot of us to
really be out there.
1976
01:24:58,227 --> 01:25:02,965
.
I'm hopeful because I'm seeing more women come into this field.
1977
01:25:02,998 --> 01:25:05,334
I'm seeing more queer
people enter this space
1978
01:25:05,401 --> 01:25:06,602
and saying like,
1979
01:25:06,635 --> 01:25:09,004
we need to really rethink
how we talk to people about sex
1980
01:25:09,071 --> 01:25:12,308
so that we include
all types of people.
1981
01:25:12,341 --> 01:25:16,011
I think that the more
pleasure and orgasms
1982
01:25:16,078 --> 01:25:18,481
and fun people can
have that is safe,
1983
01:25:18,514 --> 01:25:19,782
that is consensual,
1984
01:25:19,815 --> 01:25:22,185
I think when we focus
on pleasure and joy,
1985
01:25:22,251 --> 01:25:27,055
then the hatred and the
trolling and the nastiness
1986
01:25:27,122 --> 01:25:28,624
and the focus on
all the negative,
1987
01:25:28,657 --> 01:25:30,826
I think it kind of
starts to go away.
1988
01:25:30,859 --> 01:25:33,362
So I think by focusing on joy,
1989
01:25:33,396 --> 01:25:35,364
I think we can make
a lot of progress.
1990
01:25:35,398 --> 01:25:40,203
The magic that happens after
someone reclaims their sexuality
1991
01:25:40,269 --> 01:25:41,870
just knows who they are,
1992
01:25:41,937 --> 01:25:44,207
takes full ownership
of their existence,
1993
01:25:44,240 --> 01:25:45,174
their bodies,
1994
01:25:45,208 --> 01:25:47,876
their birthright of pleasure.
1995
01:25:47,943 --> 01:25:50,879
You get to literally
witness this person
1996
01:25:50,913 --> 01:25:52,415
step into their power.
1997
01:25:52,481 --> 01:25:54,517
I have seen so many
of my patients
1998
01:25:54,550 --> 01:25:55,851
go on to sign a book deal,
1999
01:25:55,884 --> 01:25:58,354
go on to like run for office,
2000
01:25:58,387 --> 01:26:01,190
to go on to do so many things
2001
01:26:01,224 --> 01:26:03,091
because they had the audacity
2002
01:26:03,158 --> 01:26:06,061
and the audaciousness to
chase their pleasure,
2003
01:26:06,094 --> 01:26:08,931
which then opened up doors to
chase all their other dreams,
2004
01:26:08,997 --> 01:26:11,200
and it is so fun.
2005
01:26:11,234 --> 01:26:13,536
Story alert.
I have a story alert.
2006
01:26:13,569 --> 01:26:15,371
I saw a patient very recently,
2007
01:26:15,404 --> 01:26:16,339
she's in her sixties,
2008
01:26:16,372 --> 01:26:18,607
twenty-five years ago
in her late thirties
2009
01:26:18,674 --> 01:26:22,445
she lost her ability to have
her three magical orgasms.
2010
01:26:22,511 --> 01:26:25,448
She used to orgasm three
powerful magical times.
2011
01:26:25,514 --> 01:26:29,252
Well, I just saw her and
she said, "Dr. Rubin,
2012
01:26:29,285 --> 01:26:31,354
"they're back!"
2013
01:26:31,454 --> 01:26:34,056
* Love heavy but I
gotta let you go
2014
01:26:34,089 --> 01:26:36,592
* Mind steady and I got
a way to let it go
2015
01:26:36,625 --> 01:26:39,262
* Love came here but
it never left so
2016
01:26:39,295 --> 01:26:41,630
* The way we look be
supervised by a pen stroke
2017
01:26:41,697 --> 01:26:44,099
* In the high note
crying in my throat
2018
01:26:44,132 --> 01:26:46,602
* Love heavy and I think
its time to let it go *
2019
01:26:46,669 --> 01:26:49,405
* Way of love but it weighs too
much and you weigh too much
2020
01:26:49,438 --> 01:26:52,408
* Staying out of touch
looking suss, huh *
2021
01:26:52,775 --> 01:26:54,377
* Put our love on a layaway
2022
01:26:54,410 --> 01:26:56,612
* Paying for it every time
I have a piece for you
2023
01:26:56,679 --> 01:26:57,713
* Peach that's sweet
2024
01:26:57,746 --> 01:26:59,448
* Bon appetit, bon appetit
2025
01:26:59,515 --> 01:27:02,351
* Just miss me... *